Gene: ENSMUSG00000014599 (Mus musculus)

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Gene Identifier
ENSMUSG00000014599
Transcript Identifier
ENSMUST00000120243
Gene Type
Coding gene
Location
3 : 107746739-107760063 : negative

Family Information

Homologous gene family
HOM03P100881
(orphan gene)
specific family

Descriptions

gene_descr
colony stimulating factor 1 (macrophage)

Identifiers

Type Value
UniprotP07141
MGI1339753

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001954
IGI
Genome Projectpositive regulation of cell-matrix adhesion
GO:0002158
IDA
Genome Projectosteoclast proliferation
GO:0002376
IEA
Genome Projectimmune system process
GO:0003006
IMP
Genome Projectdevelopmental process involved in reproduction
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007169
ISO
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0008284
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0010628
ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0010744
ISO
IEA
Genome Projectpositive regulation of macrophage derived foam cell differentiation
GO:0010759
ISO
Genome Projectpositive regulation of macrophage chemotaxis
GO:0030278
IMP
Genome Projectregulation of ossification
GO:0030316
ISO
IEA
Genome Projectosteoclast differentiation
GO:0030335
IGI
Genome Projectpositive regulation of cell migration
GO:0032270
ISO
IEA
Genome Projectpositive regulation of cellular protein metabolic process
GO:0032946
ISO
IEA
Genome Projectpositive regulation of mononuclear cell proliferation
GO:0038145
IDA
Genome Projectmacrophage colony-stimulating factor signaling pathway
GO:0040018
IMP
Genome Projectpositive regulation of multicellular organism growth
GO:0042488
IMP
Genome Projectpositive regulation of odontogenesis of dentin-containing tooth
GO:0045087
IEA
Genome Projectinnate immune response
GO:0045651
IMP
ISO
IEA
Genome Projectpositive regulation of macrophage differentiation
GO:0045657
IMP
Genome Projectpositive regulation of monocyte differentiation
GO:0045672
IDA, IMP, IGI
ISO
IEA
Genome Projectpositive regulation of osteoclast differentiation
GO:0045860
IGI
Genome Projectpositive regulation of protein kinase activity
GO:0046579
IDA
Genome Projectpositive regulation of Ras protein signal transduction
GO:0048873
IMP
Genome Projecthomeostasis of number of cells within a tissue
GO:0060444
IMP
Genome Projectbranching involved in mammary gland duct morphogenesis
GO:0060611
IMP
Genome Projectmammary gland fat development
GO:0060763
IMP
Genome Projectmammary duct terminal end bud growth
GO:1902228
ISO
Genome Projectpositive regulation of macrophage colony-stimulating factor signaling pathway
GO:1904141
ISO
Genome Projectpositive regulation of microglial cell migration

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
ISO
IEA
Genome Projectcytokine activity
GO:0005157
IPI
Genome Projectmacrophage colony-stimulating factor receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008083
ISO
IEA
Genome Projectgrowth factor activity
GO:0042803
IPI
ISO
IEA
Genome Projectprotein homodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0048471
ISO
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:1990682
IDA
Genome ProjectCSF1-CSF1R complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR008001Macrophage colony stimulating factor-1
IPR009079Four-helical cytokine-like, core

No MapMan annotations defined for this gene.