Gene: ENSMUSG00000010175 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000010175
Transcript Identifier
ENSMUST00000177288
Gene Type
Coding gene
Location
1 : 190123220-190162246 : negative

Family Information

Homologous gene family
HOM03P013933
(6 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P070309
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
prospero homeobox 1

Identifiers

Type Value
UniprotP48437
MGI97772

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001709
IMP
Genome Projectcell fate determination
GO:0001822
IEA
Genome Projectkidney development
GO:0001889
IEA
Genome Projectliver development
GO:0001938
ISO
IEA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0001945
IMP
Genome Projectlymph vessel development
GO:0001946
ISO
IEA
Genome Projectlymphangiogenesis
GO:0002088
IEA
Genome Projectlens development in camera-type eye
GO:0002089
IMP
Genome Projectlens morphogenesis in camera-type eye
GO:0002194
IMP
Genome Projecthepatocyte cell migration
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007420
IEA
Genome Projectbrain development
GO:0007623
IEP
Genome Projectcircadian rhythm
GO:0008284
IMP
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IMP
ISO
IEA
Genome Projectnegative regulation of cell proliferation
GO:0010468
IMP
ISO
IEA
Genome Projectregulation of gene expression
GO:0010595
ISO
IEA
Genome Projectpositive regulation of endothelial cell migration
GO:0021542
IMP
Genome Projectdentate gyrus development
GO:0021707
IMP
Genome Projectcerebellar granule cell differentiation
GO:0030240
IMP
Genome Projectskeletal muscle thin filament assembly
GO:0030324
IEA
Genome Projectlung development
GO:0031016
IEA
Genome Projectpancreas development
GO:0031667
IEA
Genome Projectresponse to nutrient levels
GO:0042752
ISS, ISO
IEA
Genome Projectregulation of circadian rhythm
GO:0043433
ISO
IEA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0045071
ISO
IEA
Genome Projectnegative regulation of viral genome replication
GO:0045446
IMP
Genome Projectendothelial cell differentiation
GO:0045737
ISO
IEA
Genome Projectpositive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045787
IMP
Genome Projectpositive regulation of cell cycle
GO:0045892
IDA
ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046619
IEP
Genome Projectoptic placode formation involved in camera-type eye formation
GO:0048511
IEA
Genome Projectrhythmic process
GO:0048839
IMP
Genome Projectinner ear development
GO:0048845
IMP
Genome Projectvenous blood vessel morphogenesis
GO:0055005
IMP
Genome Projectventricular cardiac myofibril assembly
GO:0055009
IMP
Genome Projectatrial cardiac muscle tissue morphogenesis
GO:0055010
IMP
Genome Projectventricular cardiac muscle tissue morphogenesis
GO:0060059
IEP
IEA
Genome Projectembryonic retina morphogenesis in camera-type eye
GO:0060214
IMP
Genome Projectendocardium formation
GO:0060298
IMP
Genome Projectpositive regulation of sarcomere organization
GO:0060412
IMP
Genome Projectventricular septum morphogenesis
GO:0060414
IMP
Genome Projectaorta smooth muscle tissue morphogenesis
GO:0060421
IMP
Genome Projectpositive regulation of heart growth
GO:0060836
IMP
ISO
IEA
Genome Projectlymphatic endothelial cell differentiation
GO:0060849
ISO
IEA
Genome Projectregulation of transcription involved in lymphatic endothelial cell fate commitment
GO:0061114
IMP
Genome Projectbranching involved in pancreas morphogenesis
GO:0070309
IMP
IEA
Genome Projectlens fiber cell morphogenesis
GO:0070365
IEP
IEA
Genome Projecthepatocyte differentiation
GO:0070858
ISO
IEA
Genome Projectnegative regulation of bile acid biosynthetic process
GO:0072574
IMP
Genome Projecthepatocyte proliferation
GO:0090425
IMP
Genome Projectacinar cell differentiation
GO:0097150
IMP
Genome Projectneuronal stem cell population maintenance
GO:1901978
IMP
Genome Projectpositive regulation of cell cycle checkpoint
GO:2000179
IMP
Genome Projectpositive regulation of neural precursor cell proliferation
GO:2000979
IMP
Genome Projectpositive regulation of forebrain neuron differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000981
IDA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001046
IDA
Genome Projectcore promoter sequence-specific DNA binding
GO:0003677
ISO
IEA
Genome ProjectDNA binding
GO:0003700
NAS
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IDA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003714
ISO
IEA
Genome Projecttranscription corepressor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016922
ISO
IEA
Genome Projectligand-dependent nuclear receptor binding
GO:0043565
IDA
Genome Projectsequence-specific DNA binding
GO:0044212
ISO
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0050692
ISO
IEA
Genome ProjectDBD domain binding
GO:0050693
ISO
IEA
Genome ProjectLBD domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISS, ISO
IEA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR009057Homeodomain-like
IPR023082Homeo-prospero domain

No MapMan annotations defined for this gene.