Gene: ENSMUSG00000009376 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000009376
Transcript Identifier
ENSMUST00000080469
Gene Type
Coding gene
Location
6 : 17491241-17571823 : positive

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P039467
(3 genes in 3 species)
specific family

Descriptions

gene_descr
met proto-oncogene

Identifiers

Type Value
UniprotF8VQL0
MGI96969

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
IPI
Genome Projectactivation of MAPK activity
GO:0001886
ISO
IEA
Genome Projectendothelial cell morphogenesis
GO:0001889
IMP
Genome Projectliver development
GO:0001890
IMP
Genome Projectplacenta development
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007169
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007420
IMP
Genome Projectbrain development
GO:0007517
IMP, IGI
Genome Projectmuscle organ development
GO:0007519
IMP
Genome Projectskeletal muscle tissue development
GO:0010629
IMP
Genome Projectnegative regulation of gene expression
GO:0010828
IMP
Genome Projectpositive regulation of glucose transport
GO:0014812
IMP
Genome Projectmuscle cell migration
GO:0014902
IMP
Genome Projectmyotube differentiation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018108
IEA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0030534
IMP
Genome Projectadult behavior
GO:0042593
IMP
Genome Projectglucose homeostasis
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046777
IDA
Genome Projectprotein autophosphorylation
GO:0048012
IDA
Genome Projecthepatocyte growth factor receptor signaling pathway
GO:0048754
ISO
IEA
Genome Projectbranching morphogenesis of an epithelial tube
GO:0050918
ISO
IEA
Genome Projectpositive chemotaxis
GO:0051450
IMP
Genome Projectmyoblast proliferation
GO:0055013
IMP
Genome Projectcardiac muscle cell development
GO:0060048
IMP
Genome Projectcardiac muscle contraction
GO:0060665
IMP
Genome Projectregulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0071526
ISO
IEA
Genome Projectsemaphorin-plexin signaling pathway
GO:0071635
IMP
Genome Projectnegative regulation of transforming growth factor beta production
GO:0072593
IMP
Genome Projectreactive oxygen species metabolic process
GO:1900407
IMP
Genome Projectregulation of cellular response to oxidative stress
GO:1900745
IMP
Genome Projectpositive regulation of p38MAPK cascade
GO:1901299
ISO
IEA
Genome Projectnegative regulation of hydrogen peroxide-mediated programmed cell death
GO:2001028
ISO
IEA
Genome Projectpositive regulation of endothelial cell chemotaxis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004713
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004714
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase activity
GO:0005008
IDA
Genome Projecthepatocyte growth factor-activated receptor activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019903
ISO
IEA
Genome Projectprotein phosphatase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009925
ISO
IEA
Genome Projectbasal plasma membrane
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001627Sema domain
IPR002165Plexin repeat
IPR002909IPT domain
IPR008266Tyrosine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR013783Immunoglobulin-like fold
IPR014756Immunoglobulin E-set
IPR015943WD40/YVTN repeat-like-containing domain
IPR016201Plexin-like fold
IPR016244Tyrosine-protein kinase, HGF/MSP receptor
IPR017441Protein kinase, ATP binding site
IPR020635Tyrosine-protein kinase, catalytic domain

No MapMan annotations defined for this gene.