Gene: ENSMUSG00000008999 (Mus musculus)

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Gene Identifier
ENSMUSG00000008999
Transcript Identifier
ENSMUST00000009143
Gene Type
Coding gene
Location
2 : 172870137-172940069 : negative

Family Information

Homologous gene family
HOM03P001000
(62 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P010583
(8 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
bone morphogenetic protein 7

Identifiers

Type Value
UniprotP23359
MGI103302

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001503
IEA
Genome Projectossification
GO:0001654
IMP
Genome Projecteye development
GO:0001656
IEA
Genome Projectmetanephros development
GO:0001657
IMP
Genome Projectureteric bud development
GO:0001707
IGI
Genome Projectmesoderm formation
GO:0001822
IMP
Genome Projectkidney development
GO:0001823
IEA
Genome Projectmesonephros development
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007389
IMP
Genome Projectpattern specification process
GO:0007411
IDA
Genome Projectaxon guidance
GO:0007435
IMP
Genome Projectsalivary gland morphogenesis
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0009880
IMP
Genome Projectembryonic pattern specification
GO:0009887
IMP
Genome Projectorgan morphogenesis
GO:0010800
ISO
IEA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0010862
ISS, ISO, IBA
Genome Projectpositive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010942
IGI
Genome Projectpositive regulation of cell death
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030326
IMP, IGI
Genome Projectembryonic limb morphogenesis
GO:0030501
ISO
IEA
Genome Projectpositive regulation of bone mineralization
GO:0030509
IDA
ISO
IEA
Genome ProjectBMP signaling pathway
GO:0030855
IMP
Genome Projectepithelial cell differentiation
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0033280
IEA
Genome Projectresponse to vitamin D
GO:0034116
ISO
IEA
Genome Projectpositive regulation of heterotypic cell-cell adhesion
GO:0034504
ISS, ISO
IEA
Genome Projectprotein localization to nucleus
GO:0035239
IDA
Genome Projecttube morphogenesis
GO:0040007
IEA
Genome Projectgrowth
GO:0042325
IEA
Genome Projectregulation of phosphorylation
GO:0042326
ISS, ISO
IEA
Genome Projectnegative regulation of phosphorylation
GO:0042475
IDA
Genome Projectodontogenesis of dentin-containing tooth
GO:0043065
IMP
Genome Projectpositive regulation of apoptotic process
GO:0043401
ISO
IEA
Genome Projectsteroid hormone mediated signaling pathway
GO:0043407
ISS, ISO
IEA
Genome Projectnegative regulation of MAP kinase activity
GO:0043408
IBA
Genome Projectregulation of MAPK cascade
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0045597
IDA
Genome Projectpositive regulation of cell differentiation
GO:0045665
IMP
ISO
IEA
Genome Projectnegative regulation of neuron differentiation
GO:0045666
IDA
Genome Projectpositive regulation of neuron differentiation
GO:0045669
ISO
IEA
Genome Projectpositive regulation of osteoblast differentiation
GO:0045746
IGI
Genome Projectnegative regulation of Notch signaling pathway
GO:0045786
ISO
IEA
Genome Projectnegative regulation of cell cycle
GO:0045839
ISS, ISO
IEA
Genome Projectnegative regulation of mitotic nuclear division
GO:0045892
ISS, ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IGI
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048468
IDA
Genome Projectcell development
GO:0048593
IMP
Genome Projectcamera-type eye morphogenesis
GO:0048596
IMP
Genome Projectembryonic camera-type eye morphogenesis
GO:0048646
IMP
Genome Projectanatomical structure formation involved in morphogenesis
GO:0048754
IDA
Genome Projectbranching morphogenesis of an epithelial tube
GO:0048762
ISS, ISO
IEA
Genome Projectmesenchymal cell differentiation
GO:0048812
IMP
ISO
IEA
Genome Projectneuron projection morphogenesis
GO:0050768
IDA
Genome Projectnegative regulation of neurogenesis
GO:0051216
IEA
Genome Projectcartilage development
GO:0060272
IMP, IGI
Genome Projectembryonic skeletal joint morphogenesis
GO:0060393
ISO
IEA
Genome Projectregulation of pathway-restricted SMAD protein phosphorylation
GO:0060395
ISS, ISO, IBA
IEA
Genome ProjectSMAD protein signal transduction
GO:0060445
IMP
Genome Projectbranching involved in salivary gland morphogenesis
GO:0060485
IMP
Genome Projectmesenchyme development
GO:0060548
ISO
IEA
Genome Projectnegative regulation of cell death
GO:0060686
IDA
Genome Projectnegative regulation of prostatic bud formation
GO:0060687
IMP
Genome Projectregulation of branching involved in prostate gland morphogenesis
GO:0070487
ISO
IEA
Genome Projectmonocyte aggregation
GO:0071773
ISO
Genome Projectcellular response to BMP stimulus
GO:0072040
IMP
Genome Projectnegative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
GO:0072125
ISS, ISO
IEA
Genome Projectnegative regulation of glomerular mesangial cell proliferation
GO:0072133
IGI
Genome Projectmetanephric mesenchyme morphogenesis
GO:0072134
IGI
Genome Projectnephrogenic mesenchyme morphogenesis
GO:0072136
IGI
Genome Projectmetanephric mesenchymal cell proliferation involved in metanephros development
GO:1900006
ISO
IEA
Genome Projectpositive regulation of dendrite development
GO:1900106
ISO
IEA
Genome Projectpositive regulation of hyaluranon cable assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
TAS, IEA
Genome Projectcytokine activity
GO:0005160
IBA
Genome Projecttransforming growth factor beta receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008083
IEA
Genome Projectgrowth factor activity
GO:0008201
IEA
Genome Projectheparin binding
GO:0070700
ISO, IBA
Genome ProjectBMP receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
ISO
IEA
Genome Projectextracellular space
GO:0031012
IEA
Genome Projectextracellular matrix
GO:0031988
IEA
Genome Projectmembrane-bounded vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001111Transforming growth factor-beta, N-terminal
IPR001839Transforming growth factor-beta, C-terminal
IPR015615Transforming growth factor-beta-related
IPR017948Transforming growth factor beta, conserved site
IPR029034Cystine-knot cytokine

No MapMan annotations defined for this gene.