Gene: ENSMUSG00000007989 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000007989
Transcript Identifier
ENSMUST00000131309
Gene Type
Coding gene
Location
14 : 65202719-65253132 : negative

Family Information

Homologous gene family
HOM03P002165
(40 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P018276
(5 genes in 2 species)
specific family

Descriptions

gene_descr
frizzled homolog 3 (Drosophila)

Identifiers

Type Value
UniprotQ61086
MGI108476

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001736
IGI
Genome Projectestablishment of planar polarity
GO:0001764
IMP
Genome Projectneuron migration
GO:0001843
IGI
Genome Projectneural tube closure
GO:0001942
IEP
Genome Projecthair follicle development
GO:0002052
IMP
Genome Projectpositive regulation of neuroblast proliferation
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007166
IEA
Genome Projectcell surface receptor signaling pathway
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007399
IEA
Genome Projectnervous system development
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0030901
IGI
Genome Projectmidbrain development
GO:0033278
IGI
Genome Projectcell proliferation in midbrain
GO:0035567
IBA
Genome Projectnon-canonical Wnt signaling pathway
GO:0036342
IMP
Genome Projectpost-anal tail morphogenesis
GO:0042472
IGI
Genome Projectinner ear morphogenesis
GO:0045976
IMP
Genome Projectnegative regulation of mitotic cell cycle, embryonic
GO:0060070
ISO, IBA
IEA
Genome Projectcanonical Wnt signaling pathway
GO:0061549
IMP
Genome Projectsympathetic ganglion development
GO:0071679
IMP
Genome Projectcommissural neuron axon guidance
GO:1900118
IMP
Genome Projectnegative regulation of execution phase of apoptosis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004888
IEA
Genome Projecttransmembrane signaling receptor activity
GO:0004930
IBA
IEA
Genome ProjectG-protein coupled receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0017147
ISO, IBA
IEA
Genome ProjectWnt-protein binding
GO:0030165
ISO
IEA
Genome ProjectPDZ domain binding
GO:0042813
IBA
IEA
Genome ProjectWnt-activated receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005886
IDA
ISO
TAS, IEA
Genome Projectplasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IBA
IEA
Genome Projectintegral component of membrane
GO:0016324
IDA
IEA
Genome Projectapical plasma membrane
GO:0016328
IDA
Genome Projectlateral plasma membrane
GO:0030424
IDA
Genome Projectaxon
GO:0030425
IDA
Genome Projectdendrite
GO:0032433
IDA
Genome Projectfilopodium tip
GO:0043025
IDA
Genome Projectneuronal cell body
GO:0045177
IDA
Genome Projectapical part of cell
GO:0048786
IDA
Genome Projectpresynaptic active zone

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000539Frizzled protein
IPR015526Frizzled/secreted frizzled-related protein
IPR017981GPCR, family 2-like
IPR020067Frizzled domain
IPR026553Frizzled-3, vertebrates

No MapMan annotations defined for this gene.