Gene: ENSMUSG00000007815 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000007815
Transcript Identifier
ENSMUST00000007959
Gene Type
Coding gene
Location
9 : 108327586-108336821 : positive

Family Information

Homologous gene family
HOM03P000013
(1389 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P009478
(9 genes in 6 species)
specific family

Descriptions

gene_descr
ras homolog gene family, member A

Identifiers

Type Value
UniprotQ9QUI0
UniprotQ4VAE6
MGI1096342

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000902
IGI
Genome Projectcell morphogenesis
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0006357
IDA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0007010
IMP
Genome Projectcytoskeleton organization
GO:0007155
IMP
Genome Projectcell adhesion
GO:0007160
IDA
Genome Projectcell-matrix adhesion
GO:0007229
TAS
Genome Projectintegrin-mediated signaling pathway
GO:0007264
IEA
Genome Projectsmall GTPase mediated signal transduction
GO:0007266
TAS
Genome ProjectRho protein signal transduction
GO:0007519
IDA
Genome Projectskeletal muscle tissue development
GO:0008064
IEA
Genome Projectregulation of actin polymerization or depolymerization
GO:0009612
IEA
Genome Projectresponse to mechanical stimulus
GO:0009749
IEA
Genome Projectresponse to glucose
GO:0010975
IDA
Genome Projectregulation of neuron projection development
GO:0021795
IMP
Genome Projectcerebral cortex cell migration
GO:0021861
IMP
Genome Projectforebrain radial glial cell differentiation
GO:0030036
IDA
Genome Projectactin cytoskeleton organization
GO:0030154
IDA
Genome Projectcell differentiation
GO:0030307
IEA
Genome Projectpositive regulation of cell growth
GO:0030334
ISS, ISO
Genome Projectregulation of cell migration
GO:0030335
IEA
Genome Projectpositive regulation of cell migration
GO:0030521
IDA
Genome Projectandrogen receptor signaling pathway
GO:0030838
IEA
Genome Projectpositive regulation of actin filament polymerization
GO:0031098
IEA
Genome Projectstress-activated protein kinase signaling cascade
GO:0032467
ISS, ISO
Genome Projectpositive regulation of cytokinesis
GO:0033144
IDA
Genome Projectnegative regulation of intracellular steroid hormone receptor signaling pathway
GO:0036089
ISS, ISO
Genome Projectcleavage furrow formation
GO:0038027
ISO
Genome Projectapolipoprotein A-I-mediated signaling pathway
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043124
IEA
Genome Projectnegative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043149
IDA
Genome Projectstress fiber assembly
GO:0043200
IEA
Genome Projectresponse to amino acid
GO:0043280
IEA
Genome Projectpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043297
IDA
ISO
Genome Projectapical junction assembly
GO:0043524
IMP
Genome Projectnegative regulation of neuron apoptotic process
GO:0043525
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0044319
ISS
Genome Projectwound healing, spreading of cells
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045665
IEA
Genome Projectnegative regulation of neuron differentiation
GO:0045666
ISO
Genome Projectpositive regulation of neuron differentiation
GO:0045727
IEA
Genome Projectpositive regulation of translation
GO:0045785
IEA
Genome Projectpositive regulation of cell adhesion
GO:0045907
IEA
Genome Projectpositive regulation of vasoconstriction
GO:0045987
IEA
Genome Projectpositive regulation of smooth muscle contraction
GO:0048812
IEA
Genome Projectneuron projection morphogenesis
GO:0050773
IEA
Genome Projectregulation of dendrite development
GO:0050919
ISO
Genome Projectnegative chemotaxis
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0051496
ISO
Genome Projectpositive regulation of stress fiber assembly
GO:0051924
IEA
Genome Projectregulation of calcium ion transport
GO:0060193
ISO
Genome Projectpositive regulation of lipase activity
GO:0060548
IEA
Genome Projectnegative regulation of cell death
GO:0071803
IGI
Genome Projectpositive regulation of podosome assembly
GO:0090307
ISO
Genome Projectmitotic spindle assembly
GO:1902766
ISS
Genome Projectskeletal muscle satellite cell migration
GO:2000177
IMP
Genome Projectregulation of neural precursor cell proliferation
GO:0002363
IMP
Genome Projectalpha-beta T cell lineage commitment
GO:0007049
IEA
Genome Projectcell cycle
GO:0032956
IMP
Genome Projectregulation of actin cytoskeleton organization
GO:0033688
IMP
Genome Projectregulation of osteoblast proliferation
GO:0043123
ISS
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043366
IMP
Genome Projectbeta selection
GO:0043931
IMP
Genome Projectossification involved in bone maturation
GO:0046638
IMP
Genome Projectpositive regulation of alpha-beta T cell differentiation
GO:0051301
IEA
Genome Projectcell division
GO:0061383
IMP
Genome Projecttrabecula morphogenesis
GO:0070507
IMP
Genome Projectregulation of microtubule cytoskeleton organization
GO:0090324
IMP
Genome Projectnegative regulation of oxidative phosphorylation
GO:1903427
IMP
Genome Projectnegative regulation of reactive oxygen species biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003924
IDA
TAS
Genome ProjectGTPase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005525
IEA
Genome ProjectGTP binding
GO:0017022
ISO
Genome Projectmyosin binding
GO:0019003
IEA
Genome ProjectGDP binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0051022
IEA
Genome ProjectRho GDP-dissociation inhibitor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IEA
Genome Projectintracellular
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IDA
Genome Projectmitochondrion
GO:0005768
ISO
Genome Projectendosome
GO:0005829
IDA
TAS, IEA
Genome Projectcytosol
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0005925
ISO
Genome Projectfocal adhesion
GO:0005938
ISS, ISO
IEA
Genome Projectcell cortex
GO:0016020
IEA
Genome Projectmembrane
GO:0030027
IDA
IEA
Genome Projectlamellipodium
GO:0030424
IEA
Genome Projectaxon
GO:0031982
ISO
Genome Projectvesicle
GO:0032587
IDA
Genome Projectruffle membrane
GO:0043296
ISO
Genome Projectapical junction complex
GO:0070062
ISO
Genome Projectextracellular exosome
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0030496
IEA
Genome Projectmidbody
GO:0032154
IEA
Genome Projectcleavage furrow
GO:0042995
IEA
Genome Projectcell projection

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001806Small GTPase superfamily
IPR003578Small GTPase superfamily, Rho type
IPR005225Small GTP-binding protein domain
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.