Gene: ENSMUSG00000007805 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000007805
Transcript Identifier
ENSMUST00000186075
Gene Type
Coding gene
Location
1 : 91801627-91802109 : positive

Family Information

Homologous gene family
HOM03P005493
(16 genes in 4 species)
specific family

Descriptions

gene_descr
twist basic helix-loop-helix transcription factor 2

Identifiers

Type Value
UniprotA5D6P6
MGI104685

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA, IGI
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001649
IMP
Genome Projectosteoblast differentiation
GO:0006357
IDA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0010838
IMP
Genome Projectpositive regulation of keratinocyte proliferation
GO:0032720
IMP, IGI
Genome Projectnegative regulation of tumor necrosis factor production
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043392
IDA
Genome Projectnegative regulation of DNA binding
GO:0044092
IDA
Genome Projectnegative regulation of molecular function
GO:0045638
IMP
Genome Projectnegative regulation of myeloid cell differentiation
GO:0045668
IMP
ISO
IEA
Genome Projectnegative regulation of osteoblast differentiation
GO:0048701
IGI
Genome Projectembryonic cranial skeleton morphogenesis
GO:0060325
IMP
Genome Projectface morphogenesis
GO:0061303
IMP
Genome Projectcornea development in camera-type eye

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001076
IDA
Genome Projecttranscription factor activity, RNA polymerase II transcription factor binding
GO:0003682
IDA
Genome Projectchromatin binding
GO:0003700
IDA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0019904
IPI
Genome Projectprotein domain specific binding
GO:0046983
IEA
Genome Projectprotein dimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005667
IPI
Genome Projecttranscription factor complex
GO:0005737
ISO
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011598Myc-type, basic helix-loop-helix (bHLH) domain

No MapMan annotations defined for this gene.