Gene: ENSMUSG00000007655 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000007655
Transcript Identifier
ENSMUST00000115456
Gene Type
Coding gene
Location
6 : 17306450-17339454 : positive

Family Information

Homologous gene family
HOM03P011276
(7 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P042841
(3 genes in 3 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
caveolin 1, caveolae protein

Identifiers

Type Value
UniprotP49817
MGI102709

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000165
IMP
Genome ProjectMAPK cascade
GO:0000188
IMP
Genome Projectinactivation of MAPK activity
GO:0001525
IGI
Genome Projectangiogenesis
GO:0001570
IMP
Genome Projectvasculogenesis
GO:0001666
IMP
Genome Projectresponse to hypoxia
GO:0001937
IMP
IEA
Genome Projectnegative regulation of endothelial cell proliferation
GO:0001938
IEA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0001960
IMP
Genome Projectnegative regulation of cytokine-mediated signaling pathway
GO:0002026
IMP
Genome Projectregulation of the force of heart contraction
GO:0002931
IMP
Genome Projectresponse to ischemia
GO:0003057
IGI
Genome Projectregulation of the force of heart contraction by chemical signal
GO:0006641
IMP
Genome Projecttriglyceride metabolic process
GO:0006816
IMP
Genome Projectcalcium ion transport
GO:0006874
IMP
IEA
Genome Projectcellular calcium ion homeostasis
GO:0006897
TAS
Genome Projectendocytosis
GO:0006940
IMP
Genome Projectregulation of smooth muscle contraction
GO:0007519
IMP
Genome Projectskeletal muscle tissue development
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0007595
IMP
Genome Projectlactation
GO:0008104
IMP
Genome Projectprotein localization
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0009267
IEA
Genome Projectcellular response to starvation
GO:0009612
IEA
Genome Projectresponse to mechanical stimulus
GO:0009617
ISO
Genome Projectresponse to bacterium
GO:0009967
IEA
Genome Projectpositive regulation of signal transduction
GO:0009968
IDA
Genome Projectnegative regulation of signal transduction
GO:0010332
IEA
Genome Projectresponse to gamma radiation
GO:0010524
IDA
Genome Projectpositive regulation of calcium ion transport into cytosol
GO:0010608
IMP
Genome Projectposttranscriptional regulation of gene expression
GO:0010628
IMP
Genome Projectpositive regulation of gene expression
GO:0010656
IEA
Genome Projectnegative regulation of muscle cell apoptotic process
GO:0010952
IMP
Genome Projectpositive regulation of peptidase activity
GO:0019065
ISO
IEA
Genome Projectreceptor-mediated endocytosis of virus by host cell
GO:0019217
IMP
Genome Projectregulation of fatty acid metabolic process
GO:0019915
IMP
Genome Projectlipid storage
GO:0030193
ISO
IEA
Genome Projectregulation of blood coagulation
GO:0030514
ISO
IEA
Genome Projectnegative regulation of BMP signaling pathway
GO:0030857
IMP
Genome Projectnegative regulation of epithelial cell differentiation
GO:0030879
IMP
Genome Projectmammary gland development
GO:0031100
IEA
Genome Projectorgan regeneration
GO:0031116
IEA
Genome Projectpositive regulation of microtubule polymerization
GO:0031295
ISS, ISO
IEA
Genome ProjectT cell costimulation
GO:0031397
IMP
ISO
IEA
Genome Projectnegative regulation of protein ubiquitination
GO:0031398
ISO
Genome Projectpositive regulation of protein ubiquitination
GO:0032091
ISO
IEA
Genome Projectnegative regulation of protein binding
GO:0032092
ISO
Genome Projectpositive regulation of protein binding
GO:0032570
ISO
IEA
Genome Projectresponse to progesterone
GO:0033137
ISO
IEA
Genome Projectnegative regulation of peptidyl-serine phosphorylation
GO:0033138
ISO
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0033344
IEA
Genome Projectcholesterol efflux
GO:0033484
IMP
Genome Projectnitric oxide homeostasis
GO:0034141
ISO
Genome Projectpositive regulation of toll-like receptor 3 signaling pathway
GO:0042060
IEA
Genome Projectwound healing
GO:0042310
IMP
Genome Projectvasoconstriction
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042524
IDA, IMP
Genome Projectnegative regulation of tyrosine phosphorylation of Stat5 protein
GO:0042632
IMP
Genome Projectcholesterol homeostasis
GO:0043407
IMP
Genome Projectnegative regulation of MAP kinase activity
GO:0043409
IMP
Genome Projectnegative regulation of MAPK cascade
GO:0043627
IDA
ISO
IEA
Genome Projectresponse to estrogen
GO:0045019
IMP
Genome Projectnegative regulation of nitric oxide biosynthetic process
GO:0045665
IEA
Genome Projectnegative regulation of neuron differentiation
GO:0045807
IEA
Genome Projectpositive regulation of endocytosis
GO:0045907
IMP
IEA
Genome Projectpositive regulation of vasoconstriction
GO:0046426
IDA, IMP, IGI
Genome Projectnegative regulation of JAK-STAT cascade
GO:0046785
IEA
Genome Projectmicrotubule polymerization
GO:0048550
ISO
IEA
Genome Projectnegative regulation of pinocytosis
GO:0048554
IMP
Genome Projectpositive regulation of metalloenzyme activity
GO:0048662
IEA
Genome Projectnegative regulation of smooth muscle cell proliferation
GO:0051001
IMP
Genome Projectnegative regulation of nitric-oxide synthase activity
GO:0051259
IDA
Genome Projectprotein oligomerization
GO:0051260
IDA
Genome Projectprotein homooligomerization
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0051480
ISO
IEA
Genome Projectcytosolic calcium ion homeostasis
GO:0051592
IDA
Genome Projectresponse to calcium ion
GO:0051899
IMP
Genome Projectmembrane depolarization
GO:0052547
IMP
Genome Projectregulation of peptidase activity
GO:0055074
IMP
Genome Projectcalcium ion homeostasis
GO:0060056
IMP
Genome Projectmammary gland involution
GO:0060355
ISO
Genome Projectpositive regulation of cell adhesion molecule production
GO:0060546
IMP
Genome Projectnegative regulation of necroptotic process
GO:0061099
IMP
ISO
IEA
Genome Projectnegative regulation of protein tyrosine kinase activity
GO:0070373
IEA
Genome Projectnegative regulation of ERK1 and ERK2 cascade
GO:0070836
IMP, IGI
ISO
IEA
Genome Projectcaveola assembly
GO:0071260
IEA
Genome Projectcellular response to mechanical stimulus
GO:0071360
ISO
Genome Projectcellular response to exogenous dsRNA
GO:0071375
IGI
Genome Projectcellular response to peptide hormone stimulus
GO:0071455
ISO
IEA
Genome Projectcellular response to hyperoxia
GO:0071560
IMP
Genome Projectcellular response to transforming growth factor beta stimulus
GO:0072584
ISO
IEA
Genome Projectcaveolin-mediated endocytosis
GO:0086091
IMP
Genome Projectregulation of heart rate by cardiac conduction
GO:0086098
IGI
Genome Projectangiotensin-activated signaling pathway involved in heart process
GO:0090090
IDA
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0090263
ISO
IEA
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:0090398
IEA
Genome Projectcellular senescence
GO:0097190
ISO
IEA
Genome Projectapoptotic signaling pathway
GO:0098903
ISO
IEA
Genome Projectregulation of membrane repolarization during action potential
GO:0098911
IMP
Genome Projectregulation of ventricular cardiac muscle cell action potential
GO:1900027
ISO
Genome Projectregulation of ruffle assembly
GO:1900085
IMP
ISO
IEA
Genome Projectnegative regulation of peptidyl-tyrosine autophosphorylation
GO:1901380
ISO
IEA
Genome Projectnegative regulation of potassium ion transmembrane transport
GO:1901844
IMP
Genome Projectregulation of cell communication by electrical coupling involved in cardiac conduction
GO:1901979
ISO
IEA
Genome Projectregulation of inward rectifier potassium channel activity
GO:1903598
IMP
Genome Projectpositive regulation of gap junction assembly
GO:2000286
ISO
IEA
Genome Projectreceptor internalization involved in canonical Wnt signaling pathway
GO:2000535
ISO
Genome Projectregulation of entry of bacterium into host cell
GO:2000811
IMP
ISO
IEA
Genome Projectnegative regulation of anoikis
GO:2001238
ISO
IEA
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway
GO:2001244
ISO
IEA
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway
GO:2001258
IEA
Genome Projectnegative regulation of cation channel activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000149
IEA
Genome ProjectSNARE binding
GO:0001179
IEA
Genome ProjectRNA polymerase I transcription factor binding
GO:0005102
ISO
IEA
Genome Projectreceptor binding
GO:0005198
ISO
IEA
Genome Projectstructural molecule activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016504
IMP
Genome Projectpeptidase activator activity
GO:0019899
ISO
IEA
Genome Projectenzyme binding
GO:0019900
IEA
Genome Projectkinase binding
GO:0019901
IPI
ISO
IEA
Genome Projectprotein kinase binding
GO:0019905
IEA
Genome Projectsyntaxin binding
GO:0030674
IDA
Genome Projectprotein binding, bridging
GO:0032947
IDA
Genome Projectprotein complex scaffold
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0044325
ISO
IEA
Genome Projection channel binding
GO:0046982
IPI
Genome Projectprotein heterodimerization activity
GO:0048365
ISO
Genome ProjectRac GTPase binding
GO:0050998
IPI
ISO
IEA
Genome Projectnitric-oxide synthase binding
GO:0051117
ISO
Genome ProjectATPase binding
GO:0070320
ISO
IEA
Genome Projectinward rectifier potassium channel inhibitor activity
GO:0097371
IEA
Genome ProjectMDM2/MDM4 family protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
ISS, ISO
IEA
Genome ProjectGolgi membrane
GO:0002080
IDA
Genome Projectacrosomal membrane
GO:0005622
ISO
IEA
Genome Projectintracellular
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005768
ISS, ISO
IEA
Genome Projectendosome
GO:0005778
IEA
Genome Projectperoxisomal membrane
GO:0005783
IDA
ISS, ISO
IEA
Genome Projectendoplasmic reticulum
GO:0005794
IDA
IEA
Genome ProjectGolgi apparatus
GO:0005811
IEA
Genome Projectlipid particle
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
IDA
ISO
IEA
Genome Projectplasma membrane
GO:0005887
IDA
Genome Projectintegral component of plasma membrane
GO:0005901
IDA
ISS, ISO
TAS, IEA
Genome Projectcaveola
GO:0005925
IDA
ISO
IEA
Genome Projectfocal adhesion
GO:0005929
IDA
Genome Projectcilium
GO:0005938
IDA
Genome Projectcell cortex
GO:0009925
IEA
Genome Projectbasal plasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0016020
IDA
ISO
IEA
Genome Projectmembrane
GO:0016021
IDA
Genome Projectintegral component of membrane
GO:0016323
ISO
IEA
Genome Projectbasolateral plasma membrane
GO:0016324
ISO
IEA
Genome Projectapical plasma membrane
GO:0031410
ISO
IEA
Genome Projectcytoplasmic vesicle
GO:0043234
IDA, IPI
ISO
IEA
Genome Projectprotein complex
GO:0045121
IDA
ISO
IEA
Genome Projectmembrane raft
GO:0048471
IDA
ISO
Genome Projectperinuclear region of cytoplasm
GO:0034098
ISO
Genome ProjectVCP-NPL4-UFD1 AAA ATPase complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001612Caveolin
IPR015504Caveolin-1
IPR018361Caveolin, conserved site

No MapMan annotations defined for this gene.