Gene: ENSMUSG00000007653 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000007653
Transcript Identifier
ENSMUST00000192403
Gene Type
Coding gene
Location
11 : 42421350-42626891 : positive

Family Information

Homologous gene family
HOM03P000436
(104 genes in 8 species)
specific family
Orthologous gene family
ORTHO03P006906
(12 genes in 5 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2

Identifiers

Type Value
UniprotP63137
MGI95620

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006821
IEA
Genome Projectchloride transport
GO:0007165
ISS
IEA
Genome Projectsignal transduction
GO:0007605
IMP
Genome Projectsensory perception of sound
GO:0043523
IMP
Genome Projectregulation of neuron apoptotic process
GO:0043524
IMP
Genome Projectnegative regulation of neuron apoptotic process
GO:0048666
IMP
Genome Projectneuron development
GO:0051932
IEA
Genome Projectsynaptic transmission, GABAergic
GO:0060119
IMP
Genome Projectinner ear receptor cell development
GO:0060384
IMP
Genome Projectinnervation
GO:0071420
ISS
IEA
Genome Projectcellular response to histamine
GO:0090102
IMP
Genome Projectcochlea development
GO:1901215
IMP
Genome Projectnegative regulation of neuron death
GO:1902476
ISS
IEA
Genome Projectchloride transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004890
ISS
IEA
Genome ProjectGABA-A receptor activity
GO:0005216
IEA
Genome Projection channel activity
GO:0005230
IEA
Genome Projectextracellular ligand-gated ion channel activity
GO:0005237
IEA
Genome Projectinhibitory extracellular ligand-gated ion channel activity
GO:0005254
ISS
IEA
Genome Projectchloride channel activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016917
IEA
Genome ProjectGABA receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0005887
ISS
IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0034707
IEA
Genome Projectchloride channel complex
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:1902710
IEA
Genome ProjectGABA receptor complex
GO:1902711
ISS
IEA
Genome ProjectGABA-A receptor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002289Gamma-aminobutyric-acid A receptor, beta subunit
IPR006028Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029Neurotransmitter-gated ion-channel transmembrane domain
IPR006201Neurotransmitter-gated ion-channel
IPR006202Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000Neurotransmitter-gated ion-channel, conserved site

No MapMan annotations defined for this gene.