Gene: ENSMUSG00000006678 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000006678
Transcript Identifier
ENSMUST00000006856
Gene Type
Coding gene
Location
X : 93305671-93632111 : negative

Family Information

Homologous gene family
HOM03P000229
(155 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P001708
(36 genes in 36 species)
specific family

Descriptions

gene_descr
polymerase (DNA directed), alpha 1

Identifiers

Type Value
UniprotP33609
MGI99660

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006260
IDA, IMP
ISS, ISO
IEA
Genome ProjectDNA replication
GO:0006261
IBA
Genome ProjectDNA-dependent DNA replication
GO:0006269
ISO
IEA
Genome ProjectDNA replication, synthesis of RNA primer
GO:0006270
ISS, ISO
IEA
Genome ProjectDNA replication initiation
GO:0006271
ISS, ISO
IEA
Genome ProjectDNA strand elongation involved in DNA replication
GO:0006272
ISS, ISO, IBA
IEA
Genome Projectleading strand elongation
GO:0006273
ISS, ISO, IBA
IEA
Genome Projectlagging strand elongation
GO:0006303
ISS, ISO, IBA
Genome Projectdouble-strand break repair via nonhomologous end joining
GO:0008283
ISS, ISO
IEA
Genome Projectcell proliferation
GO:0071897
ISO
IEA
Genome ProjectDNA biosynthetic process
GO:0090305
IEA
Genome Projectnucleic acid phosphodiester bond hydrolysis
GO:0000731
ISS
Genome ProjectDNA synthesis involved in DNA repair
GO:0006281
ISS
Genome ProjectDNA repair

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
ISS, ISO
IEA
Genome Projectnucleotide binding
GO:0001882
IEA
Genome Projectnucleoside binding
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003677
ISS, ISO
IEA
Genome ProjectDNA binding
GO:0003682
ISS, ISO
IEA
Genome Projectchromatin binding
GO:0003887
IDA
ISS, ISO
IEA
Genome ProjectDNA-directed DNA polymerase activity
GO:0003896
ISS, ISO
IEA
Genome ProjectDNA primase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008408
IEA
Genome Project3'-5' exonuclease activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016779
IEA
Genome Projectnucleotidyltransferase activity
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
IPI
Genome Projectprotein heterodimerization activity
GO:0051536
IEA
Genome Projectiron-sulfur cluster binding
GO:0051539
IEA
Genome Project4 iron, 4 sulfur cluster binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000785
ISS, ISO
IEA
Genome Projectchromatin
GO:0005634
IDA
ISS, ISO
IEA
Genome Projectnucleus
GO:0005635
ISS, ISO
IEA
Genome Projectnuclear envelope
GO:0005654
ISS, ISO
IEA
Genome Projectnucleoplasm
GO:0005658
IDA
ISS, ISO
IEA
Genome Projectalpha DNA polymerase:primase complex
GO:0005730
ISS, ISO
IEA
Genome Projectnucleolus
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0016363
ISS, ISO
IEA
Genome Projectnuclear matrix

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR006133DNA-directed DNA polymerase, family B, exonuclease domain
IPR006134DNA-directed DNA polymerase, family B, multifunctional domain
IPR006172DNA-directed DNA polymerase, family B
IPR012337Ribonuclease H-like domain
IPR015088Zinc finger, DNA-directed DNA polymerase, family B, alpha
IPR017964DNA-directed DNA polymerase, family B, conserved site
IPR023211DNA polymerase, palm domain
IPR024647DNA polymerase alpha catalytic subunit, N-terminal domain
IPR029702DNA polymerase alpha catalytic subunit

No MapMan annotations defined for this gene.