Gene: ENSMUSG00000006494 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000006494
Transcript Identifier
ENSMUST00000006669
Gene Type
Coding gene
Location
2 : 71873370-71900124 : positive

Family Information

Homologous gene family
HOM03P000760
(74 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P000781
(43 genes in 36 species)
specific family

Descriptions

gene_descr
pyruvate dehydrogenase kinase, isoenzyme 1

Identifiers

Type Value
UniprotQ8BFP9
MGI1926119

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005975
IEA
Genome Projectcarbohydrate metabolic process
GO:0006006
IEA
Genome Projectglucose metabolic process
GO:0006468
ISO
Genome Projectprotein phosphorylation
GO:0008283
ISS, ISO
IEA
Genome Projectcell proliferation
GO:0008631
ISS, ISO
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to oxidative stress
GO:0010510
IMP
Genome Projectregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010906
ISS, ISO
IEA
Genome Projectregulation of glucose metabolic process
GO:0016310
IEA
Genome Projectphosphorylation
GO:0035556
ISA
Genome Projectintracellular signal transduction
GO:0097411
ISS, ISO
IEA
Genome Projecthypoxia-inducible factor-1alpha signaling pathway
GO:0098779
ISO
Genome Projectmitophagy in response to mitochondrial depolarization
GO:1903146
IEA
Genome Projectregulation of mitophagy

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
ISO
IEA
Genome Projectprotein kinase activity
GO:0004740
ISS, ISO
IEA
Genome Projectpyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005759
IEA
Genome Projectmitochondrial matrix
GO:0005886
ISA
Genome Projectplasma membrane
GO:0005967
IDA
Genome Projectmitochondrial pyruvate dehydrogenase complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR003594Histidine kinase-like ATPase, C-terminal domain
IPR005467Histidine kinase domain
IPR018955Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal

No MapMan annotations defined for this gene.