Gene: ENSMUSG00000006457 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000006457
Transcript Identifier
ENSMUST00000006626
Gene Type
Coding gene
Location
19 : 4861345-4877854 : negative

Family Information

Homologous gene family
HOM03P000481
(99 genes in 11 species)
specific family
Orthologous gene family
ORTHO03P006041
(14 genes in 10 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
actinin alpha 3

Identifiers

Type Value
UniprotO88990
MGI99678

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006936
IDA
Genome Projectmuscle contraction
GO:0014728
IMP
Genome Projectregulation of the force of skeletal muscle contraction
GO:0014732
IMP
Genome Projectskeletal muscle atrophy
GO:0014883
IMP
Genome Projecttransition between fast and slow fiber
GO:0014894
IMP
Genome Projectresponse to denervation involved in regulation of muscle adaptation
GO:0031448
IMP
Genome Projectpositive regulation of fast-twitch skeletal muscle fiber contraction
GO:0045820
IMP
Genome Projectnegative regulation of glycolytic process
GO:0048633
IMP
Genome Projectpositive regulation of skeletal muscle tissue growth
GO:0048743
IMP
Genome Projectpositive regulation of skeletal muscle fiber development
GO:0060349
IMP
Genome Projectbone morphogenesis
GO:0070885
IMP
Genome Projectnegative regulation of calcineurin-NFAT signaling cascade
GO:0090257
IMP
Genome Projectregulation of muscle system process
GO:0090324
IMP
Genome Projectnegative regulation of oxidative phosphorylation
GO:1900159
IMP
Genome Projectpositive regulation of bone mineralization involved in bone maturation
GO:1901078
IMP
Genome Projectnegative regulation of relaxation of muscle
GO:1903715
IMP
Genome Projectregulation of aerobic respiration
GO:1904025
IMP
Genome Projectpositive regulation of glucose catabolic process to lactate via pyruvate
GO:0001649
IMP
Genome Projectosteoblast differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003779
IEA
Genome Projectactin binding
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0030674
TAS
Genome Projectprotein binding, bridging
GO:0042803
TAS
Genome Projectprotein homodimerization activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051015
IDA
TAS
Genome Projectactin filament binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IDA
Genome Projectintracellular
GO:0005865
TAS
Genome Projectstriated muscle thin filament
GO:0005903
IDA
Genome Projectbrush border
GO:0030017
IDA
Genome Projectsarcomere
GO:0030018
IDA
Genome ProjectZ disc

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001589Actinin-type actin-binding domain, conserved site
IPR001715Calponin homology domain
IPR002017Spectrin repeat
IPR002048EF-hand domain
IPR011992EF-hand domain pair
IPR014837EF-hand, Ca insensitive
IPR018159Spectrin/alpha-actinin

No MapMan annotations defined for this gene.