Gene: ENSMUSG00000005871 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000005871
Transcript Identifier
ENSMUST00000079362
Gene Type
Coding gene
Location
18 : 34261023-34318581 : positive

Family Information

Homologous gene family
HOM03P013209
(6 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P029792
(3 genes in 2 species)
specific family

Descriptions

gene_descr
adenomatosis polyposis coli

Identifiers

Type Value
UniprotB2RUG9
MGI88039

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000281
IMP
ISO
IEA
Genome Projectmitotic cytokinesis
GO:0001822
IMP
Genome Projectkidney development
GO:0001942
IMP
Genome Projecthair follicle development
GO:0006461
ISO
IEA
Genome Projectprotein complex assembly
GO:0006974
ISO
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007026
IMP
ISO
IEA
Genome Projectnegative regulation of microtubule depolymerization
GO:0007050
ISO
IEA
Genome Projectcell cycle arrest
GO:0007091
IMP, IGI
Genome Projectmetaphase/anaphase transition of mitotic cell cycle
GO:0007094
ISO
IEA
Genome Projectmitotic spindle assembly checkpoint
GO:0007389
IMP
Genome Projectpattern specification process
GO:0007409
IMP, IGI
Genome Projectaxonogenesis
GO:0008285
IMP, IGI
ISO
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009798
IMP
Genome Projectaxis specification
GO:0009952
IMP
Genome Projectanterior/posterior pattern specification
GO:0009953
IMP
Genome Projectdorsal/ventral pattern formation
GO:0009954
IMP
Genome Projectproximal/distal pattern formation
GO:0016055
IDA, IMP
IEA
Genome ProjectWnt signaling pathway
GO:0016477
IMP
ISO
IEA
Genome Projectcell migration
GO:0019827
IMP
Genome Projectstem cell population maintenance
GO:0030178
IMP, IGI
IEA
Genome Projectnegative regulation of Wnt signaling pathway
GO:0030334
IMP, IGI
Genome Projectregulation of cell migration
GO:0030335
IMP
ISO
IEA
Genome Projectpositive regulation of cell migration
GO:0030856
IMP
Genome Projectregulation of epithelial cell differentiation
GO:0030858
IGI
Genome Projectpositive regulation of epithelial cell differentiation
GO:0031116
IMP
Genome Projectpositive regulation of microtubule polymerization
GO:0031122
IGI
Genome Projectcytoplasmic microtubule organization
GO:0031274
ISO
IEA
Genome Projectpositive regulation of pseudopodium assembly
GO:0032886
ISO
IEA
Genome Projectregulation of microtubule-based process
GO:0033077
IMP
Genome ProjectT cell differentiation in thymus
GO:0035019
IMP, IGI
Genome Projectsomatic stem cell population maintenance
GO:0042483
IMP
Genome Projectnegative regulation of odontogenesis
GO:0043065
IMP
ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043066
IMP
Genome Projectnegative regulation of apoptotic process
GO:0043409
IMP, IGI
Genome Projectnegative regulation of MAPK cascade
GO:0043588
IMP
Genome Projectskin development
GO:0044336
IGI
Genome Projectcanonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0044337
IGI
Genome Projectcanonical Wnt signaling pathway involved in positive regulation of apoptotic process
GO:0045595
IGI
Genome Projectregulation of cell differentiation
GO:0045597
IMP
Genome Projectpositive regulation of cell differentiation
GO:0045667
IMP
Genome Projectregulation of osteoblast differentiation
GO:0045670
IMP
Genome Projectregulation of osteoclast differentiation
GO:0045732
IMP
ISO
IEA
Genome Projectpositive regulation of protein catabolic process
GO:0045736
ISO
IEA
Genome Projectnegative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045785
IMP
Genome Projectpositive regulation of cell adhesion
GO:0046716
IGI
Genome Projectmuscle cell cellular homeostasis
GO:0048538
IMP
Genome Projectthymus development
GO:0050680
IMP, IGI
Genome Projectnegative regulation of epithelial cell proliferation
GO:0051171
IMP
Genome Projectregulation of nitrogen compound metabolic process
GO:0051276
IMP, IGI
Genome Projectchromosome organization
GO:0051726
IMP
Genome Projectregulation of cell cycle
GO:0051781
IMP
Genome Projectpositive regulation of cell division
GO:0051988
IMP
ISO
Genome Projectregulation of attachment of spindle microtubules to kinetochore
GO:0060041
IMP
Genome Projectretina development in camera-type eye
GO:0060070
IMP
Genome Projectcanonical Wnt signaling pathway
GO:0060770
IMP
Genome Projectnegative regulation of epithelial cell proliferation involved in prostate gland development
GO:0090090
IMP
ISO
IEA
Genome Projectnegative regulation of canonical Wnt signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008013
IDA, IPI
ISO
IEA
Genome Projectbeta-catenin binding
GO:0008017
ISO
IEA
Genome Projectmicrotubule binding
GO:0019887
ISO
IEA
Genome Projectprotein kinase regulator activity
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0045295
ISO
IEA
Genome Projectgamma-catenin binding
GO:0051010
IDA
ISO
IEA
Genome Projectmicrotubule plus-end binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000776
ISO
IEA
Genome Projectkinetochore
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005813
ISO
IEA
Genome Projectcentrosome
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0005913
ISO
IEA
Genome Projectcell-cell adherens junction
GO:0005923
ISO
IEA
Genome Projectbicellular tight junction
GO:0016328
ISO
IEA
Genome Projectlateral plasma membrane
GO:0016342
ISO
IEA
Genome Projectcatenin complex
GO:0030027
ISO
IEA
Genome Projectlamellipodium
GO:0030424
IDA
Genome Projectaxon
GO:0030426
IDA
Genome Projectgrowth cone
GO:0030877
ISO
IEA
Genome Projectbeta-catenin destruction complex
GO:0031253
IDA
Genome Projectcell projection membrane
GO:0032587
ISO
IEA
Genome Projectruffle membrane
GO:0042995
IDA
Genome Projectcell projection
GO:0044295
IDA
Genome Projectaxonal growth cone
GO:0005881
IDA
Genome Projectcytoplasmic microtubule
GO:0035371
IDA
Genome Projectmicrotubule plus-end

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000225Armadillo
IPR009223Adenomatous polyposis coli protein, cysteine-rich repeat
IPR009224SAMP
IPR009232EB-1 binding
IPR009234Adenomatous polyposis coli protein basic domain
IPR009240Adenomatous polyposis coli protein, 15 residue repeat
IPR011989Armadillo-like helical
IPR016024Armadillo-type fold
IPR026818Adenomatous polyposis coli (APC) family
IPR026831Adenomatous polyposis coli protein
IPR026836Adenomatous polyposis coli
IPR032038Adenomatous polyposis coli, N-terminal dimerisation domain

No MapMan annotations defined for this gene.