Gene: ENSMUSG00000005583 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000005583
Transcript Identifier
ENSMUST00000163888
Gene Type
Coding gene
Location
13 : 83575677-83662631 : positive

Family Information

Homologous gene family
HOM03P000139
(214 genes in 26 species)
specific family
Orthologous gene family
ORTHO03P071894
(2 genes in 2 species)
specific family

Descriptions

gene_descr
myocyte enhancer factor 2C

Identifiers

Type Value
UniprotQ8CFN5
MGI99458

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IGI
ISS, ISO
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000165
IDA, IMP
ISO
Genome ProjectMAPK cascade
GO:0001568
IMP
Genome Projectblood vessel development
GO:0001649
IGI, IEP
Genome Projectosteoblast differentiation
GO:0001764
IMP
Genome Projectneuron migration
GO:0001782
IMP
Genome ProjectB cell homeostasis
GO:0001947
IMP
Genome Projectheart looping
GO:0001958
IMP, IGI
Genome Projectendochondral ossification
GO:0001974
IMP
Genome Projectblood vessel remodeling
GO:0002062
IGI
Genome Projectchondrocyte differentiation
GO:0002467
IMP
Genome Projectgerminal center formation
GO:0002634
IMP
Genome Projectregulation of germinal center formation
GO:0002931
ISS
Genome Projectresponse to ischemia
GO:0003138
IMP
Genome Projectprimary heart field specification
GO:0003139
IMP
Genome Projectsecondary heart field specification
GO:0003151
IGI
Genome Projectoutflow tract morphogenesis
GO:0003185
IMP
Genome Projectsinoatrial valve morphogenesis
GO:0003211
IMP, IGI
Genome Projectcardiac ventricle formation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IDA
ISO
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
ISO
Genome Projecttranscription from RNA polymerase II promoter
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006959
IMP
Genome Projecthumoral immune response
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007399
IEA
Genome Projectnervous system development
GO:0007507
IMP
Genome Projectheart development
GO:0007519
IMP
Genome Projectskeletal muscle tissue development
GO:0007521
IMP
Genome Projectmuscle cell fate determination
GO:0007611
IMP
Genome Projectlearning or memory
GO:0010628
IDA, IMP
ISO
Genome Projectpositive regulation of gene expression
GO:0010629
IMP
Genome Projectnegative regulation of gene expression
GO:0010694
IMP
Genome Projectpositive regulation of alkaline phosphatase activity
GO:0014033
IMP
Genome Projectneural crest cell differentiation
GO:0014898
IMP
Genome Projectcardiac muscle hypertrophy in response to stress
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030182
IMP
Genome Projectneuron differentiation
GO:0030220
IMP
Genome Projectplatelet formation
GO:0030224
IMP
Genome Projectmonocyte differentiation
GO:0030279
ISS, ISO
Genome Projectnegative regulation of ossification
GO:0030318
IMP
Genome Projectmelanocyte differentiation
GO:0030501
IMP
Genome Projectpositive regulation of bone mineralization
GO:0030890
IMP
Genome Projectpositive regulation of B cell proliferation
GO:0035690
IDA
Genome Projectcellular response to drug
GO:0035914
IMP
NAS
Genome Projectskeletal muscle cell differentiation
GO:0035984
IDA
Genome Projectcellular response to trichostatin A
GO:0042100
IMP
Genome ProjectB cell proliferation
GO:0043406
ISS
Genome Projectpositive regulation of MAP kinase activity
GO:0043523
IMP
Genome Projectregulation of neuron apoptotic process
GO:0043524
IDA
Genome Projectnegative regulation of neuron apoptotic process
GO:0045165
IMP
Genome Projectcell fate commitment
GO:0045652
IMP
Genome Projectregulation of megakaryocyte differentiation
GO:0045663
ISS, ISO
Genome Projectpositive regulation of myoblast differentiation
GO:0045666
IDA
Genome Projectpositive regulation of neuron differentiation
GO:0045669
IMP
Genome Projectpositive regulation of osteoblast differentiation
GO:0045893
IDA, IMP
ISO
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA, IMP, IGI
ISO
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046928
IMP
Genome Projectregulation of neurotransmitter secretion
GO:0048167
IMP
Genome Projectregulation of synaptic plasticity
GO:0048643
ISS, ISO
Genome Projectpositive regulation of skeletal muscle tissue development
GO:0048666
IMP
Genome Projectneuron development
GO:0048667
IMP
Genome Projectcell morphogenesis involved in neuron differentiation
GO:0048703
IMP
Genome Projectembryonic viscerocranium morphogenesis
GO:0048704
IMP
Genome Projectembryonic skeletal system morphogenesis
GO:0050680
IMP
Genome Projectnegative regulation of epithelial cell proliferation
GO:0050853
IMP
Genome ProjectB cell receptor signaling pathway
GO:0051145
IMP
Genome Projectsmooth muscle cell differentiation
GO:0051963
IMP
Genome Projectregulation of synapse assembly
GO:0051966
IMP
Genome Projectregulation of synaptic transmission, glutamatergic
GO:0055007
IGI
NAS
Genome Projectcardiac muscle cell differentiation
GO:0055012
IMP
Genome Projectventricular cardiac muscle cell differentiation
GO:0060021
IGI
Genome Projectpalate development
GO:0060025
IMP
Genome Projectregulation of synaptic activity
GO:0060045
IMP
Genome Projectpositive regulation of cardiac muscle cell proliferation
GO:0060079
IMP
Genome Projectexcitatory postsynaptic potential
GO:0060297
IMP
Genome Projectregulation of sarcomere organization
GO:0060536
IMP
Genome Projectcartilage morphogenesis
GO:0060998
IMP
Genome Projectregulation of dendritic spine development
GO:0061333
IMP
Genome Projectrenal tubule morphogenesis
GO:0071222
IDA
Genome Projectcellular response to lipopolysaccharide
GO:0071277
IDA
Genome Projectcellular response to calcium ion
GO:0071374
ISS, ISO
Genome Projectcellular response to parathyroid hormone stimulus
GO:0071498
IDA
Genome Projectcellular response to fluid shear stress
GO:0071560
ISS, ISO
Genome Projectcellular response to transforming growth factor beta stimulus
GO:0071864
IGI
Genome Projectpositive regulation of cell proliferation in bone marrow
GO:0072102
IMP
Genome Projectglomerulus morphogenesis
GO:0072160
IMP
Genome Projectnephron tubule epithelial cell differentiation
GO:0090073
IDA
Genome Projectpositive regulation of protein homodimerization activity
GO:2000111
IMP
Genome Projectpositive regulation of macrophage apoptotic process
GO:2000310
IMP
Genome Projectregulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000311
IMP
Genome Projectregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000727
IMP
ISO
Genome Projectpositive regulation of cardiac muscle cell differentiation
GO:2000987
IMP
Genome Projectpositive regulation of behavioral fear response
GO:2001013
IMP
Genome Projectepithelial cell proliferation involved in renal tubule morphogenesis
GO:2001016
ISO
Genome Projectpositive regulation of skeletal muscle cell differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IDA
ISO
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978
IDA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980
IDA
Genome ProjectRNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981
IDA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0000983
ISS, ISO
Genome Projecttranscription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987
IDA
Genome Projectcore promoter proximal region sequence-specific DNA binding
GO:0001046
IDA
Genome Projectcore promoter sequence-specific DNA binding
GO:0001077
IDA, IMP
ISO
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001205
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003677
IDA
ISO
IEA
Genome ProjectDNA binding
GO:0003680
ISO
Genome ProjectAT DNA binding
GO:0003682
IDA
Genome Projectchromatin binding
GO:0003700
IDA
ISO
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IDA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0033613
ISO
Genome Projectactivating transcription factor binding
GO:0035198
ISS, ISO
Genome ProjectmiRNA binding
GO:0042826
IPI
Genome Projecthistone deacetylase binding
GO:0043565
IDA
Genome Projectsequence-specific DNA binding
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0046982
ISO
Genome Projectprotein heterodimerization activity
GO:0046983
IEA
Genome Projectprotein dimerization activity
GO:0071837
IPI
Genome ProjectHMG box domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IC, IEA
Genome Projectnucleus
GO:0005654
ISO
Genome Projectnucleoplasm
GO:0005737
ISS, ISO
Genome Projectcytoplasm
GO:0005829
ISS
Genome Projectcytosol
GO:0016607
ISS, ISO
Genome Projectnuclear speck
GO:0043231
ISO
Genome Projectintracellular membrane-bounded organelle
GO:0043234
ISS, ISO
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002100Transcription factor, MADS-box
IPR022102Holliday junction regulator protein family C-terminal

No MapMan annotations defined for this gene.