Gene: ENSMUSG00000005469 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000005469
Transcript Identifier
ENSMUST00000005606
Gene Type
Coding gene
Location
8 : 83973187-83995417 : positive

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000331
(54 genes in 23 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
protein kinase, cAMP dependent, catalytic, alpha

Identifiers

Type Value
UniprotP05132
MGI97592

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001707
IGI
Genome Projectmesoderm formation
GO:0001843
IGI
Genome Projectneural tube closure
GO:0006468
IDA
IEA
Genome Projectprotein phosphorylation
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018105
IDA
ISO
IEA
Genome Projectpeptidyl-serine phosphorylation
GO:0018107
IDA
Genome Projectpeptidyl-threonine phosphorylation
GO:0043457
IEA
Genome Projectregulation of cellular respiration
GO:0045667
ISO
IEA
Genome Projectregulation of osteoblast differentiation
GO:0046777
IDA
Genome Projectprotein autophosphorylation
GO:0046827
IMP
Genome Projectpositive regulation of protein export from nucleus
GO:0048240
IDA
Genome Projectsperm capacitation
GO:0050804
IMP
Genome Projectmodulation of synaptic transmission
GO:0051447
IEA
Genome Projectnegative regulation of meiotic cell cycle
GO:0051966
IEA
Genome Projectregulation of synaptic transmission, glutamatergic
GO:0061136
ISO
IEA
Genome Projectregulation of proteasomal protein catabolic process
GO:0070613
IGI
Genome Projectregulation of protein processing
GO:0071158
IDA
Genome Projectpositive regulation of cell cycle arrest
GO:0071333
ISO
IEA
Genome Projectcellular response to glucose stimulus
GO:0071374
IMP
Genome Projectcellular response to parathyroid hormone stimulus
GO:1901621
IGI
Genome Projectnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:2000810
ISO
IEA
Genome Projectregulation of bicellular tight junction assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004691
IDA
ISO
IEA
Genome ProjectcAMP-dependent protein kinase activity
GO:0004712
ISO
IEA
Genome Projectprotein serine/threonine/tyrosine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0034237
ISO
IEA
Genome Projectprotein kinase A regulatory subunit binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005813
ISO
IEA
Genome Projectcentrosome
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0005929
IEA
Genome Projectcilium
GO:0005952
IEA
Genome ProjectcAMP-dependent protein kinase complex
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0031514
IEA
Genome Projectmotile cilium
GO:0031588
ISO
IEA
Genome Projectnucleotide-activated protein kinase complex
GO:0031594
IDA
Genome Projectneuromuscular junction
GO:0042995
IEA
Genome Projectcell projection
GO:0043005
IEA
Genome Projectneuron projection
GO:0043234
IEA
Genome Projectprotein complex
GO:0044853
ISO
Genome Projectplasma membrane raft
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0097225
ISS, ISO
IEA
Genome Projectsperm midpiece
GO:0097546
IDA
Genome Projectciliary base

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.