Gene: ENSMUSG00000004951 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000004951
Transcript Identifier
ENSMUST00000005077
Gene Type
Coding gene
Location
5 : 135888059-135889430 : positive

Family Information

Homologous gene family
HOM03P002488
(37 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P069238
(2 genes in 2 species)
specific family

Descriptions

gene_descr
heat shock protein 1

Identifiers

Type Value
UniprotP14602
UniprotQ545F4
MGI96240

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001895
IEA
Genome Projectretina homeostasis
GO:0006469
IDA
Genome Projectnegative regulation of protein kinase activity
GO:0006986
NAS
Genome Projectresponse to unfolded protein
GO:0009615
ISS
IEA
Genome Projectresponse to virus
GO:0032731
IDA
Genome Projectpositive regulation of interleukin-1 beta production
GO:0035556
ISO
IEA
Genome Projectintracellular signal transduction
GO:0035924
ISO
IEA
Genome Projectcellular response to vascular endothelial growth factor stimulus
GO:0038033
ISO
IEA
Genome Projectpositive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0042535
IDA
Genome Projectpositive regulation of tumor necrosis factor biosynthetic process
GO:0043122
IDA
Genome Projectregulation of I-kappaB kinase/NF-kappaB signaling
GO:0043536
ISO
IEA
Genome Projectpositive regulation of blood vessel endothelial cell migration
GO:0045766
ISO
IEA
Genome Projectpositive regulation of angiogenesis
GO:0070527
ISO
IEA
Genome Projectplatelet aggregation
GO:0071901
IDA
Genome Projectnegative regulation of protein serine/threonine kinase activity
GO:1902176
IDA
Genome Projectnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:2001028
ISO
IEA
Genome Projectpositive regulation of endothelial cell chemotaxis
GO:2001234
IDA
Genome Projectnegative regulation of apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005080
IDA
Genome Projectprotein kinase C binding
GO:0008426
IDA
Genome Projectprotein kinase C inhibitor activity
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0043130
ISS
Genome Projectubiquitin binding
GO:0044822
ISO
IEA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000502
ISS
Genome Projectproteasome complex
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005622
IDA
Genome Projectintracellular
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005819
IEA
Genome Projectspindle
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
IDA
Genome Projectplasma membrane
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0030018
IDA
Genome ProjectZ disc
GO:0043292
IDA
Genome Projectcontractile fiber
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001436Alpha crystallin/Heat shock protein
IPR002068Alpha crystallin/Hsp20 domain
IPR008978HSP20-like chaperone
IPR031107Small heat shock protein HSP20

No MapMan annotations defined for this gene.