Gene: ENSMUSG00000004654 (Mus musculus)

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Gene Identifier
ENSMUSG00000004654
Transcript Identifier
ENSMUST00000063578
Gene Type
Coding gene
Location
6 : 55376385-55388294 : positive

Family Information

Homologous gene family
HOM03P002772
(34 genes in 4 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
growth hormone releasing hormone receptor

Identifiers

Type Value
UniprotP32082
MGI95710

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007166
IEA
Genome Projectcell surface receptor signaling pathway
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007188
IEA
Genome Projectadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189
IMP, IGI
ISO
IEA
Genome Projectadenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190
IEA
Genome Projectactivation of adenylate cyclase activity
GO:0007595
IMP
Genome Projectlactation
GO:0008284
IMP
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008340
IMP
Genome Projectdetermination of adult lifespan
GO:0019933
ISO
IEA
Genome ProjectcAMP-mediated signaling
GO:0021984
IMP
Genome Projectadenohypophysis development
GO:0030104
IGI
Genome Projectwater homeostasis
GO:0030252
IMP
Genome Projectgrowth hormone secretion
GO:0030816
IEA
Genome Projectpositive regulation of cAMP metabolic process
GO:0030819
ISO
IEA
Genome Projectpositive regulation of cAMP biosynthetic process
GO:0030879
IMP
Genome Projectmammary gland development
GO:0032868
ISO
IEA
Genome Projectresponse to insulin
GO:0032869
IDA
Genome Projectcellular response to insulin stimulus
GO:0033143
IMP
Genome Projectregulation of intracellular steroid hormone receptor signaling pathway
GO:0040018
IMP, IGI
ISO
IEA
Genome Projectpositive regulation of multicellular organism growth
GO:0042445
IMP
Genome Projecthormone metabolic process
GO:0043567
IMP
Genome Projectregulation of insulin-like growth factor receptor signaling pathway
GO:0043627
ISO
IEA
Genome Projectresponse to estrogen
GO:0046887
IMP
Genome Projectpositive regulation of hormone secretion
GO:0048469
IMP
Genome Projectcell maturation
GO:0051246
IGI
Genome Projectregulation of protein metabolic process
GO:0051384
ISO
IEA
Genome Projectresponse to glucocorticoid
GO:0060124
IMP
Genome Projectpositive regulation of growth hormone secretion
GO:0060133
IMP
Genome Projectsomatotropin secreting cell development

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004888
IEA
Genome Projecttransmembrane signaling receptor activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016520
IMP, IGI
ISO
IEA
Genome Projectgrowth hormone-releasing hormone receptor activity
GO:0017046
IPI
ISO
IEA
Genome Projectpeptide hormone binding
GO:0019838
ISO
IEA
Genome Projectgrowth factor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005637
ISO
IEA
Genome Projectnuclear inner membrane
GO:0005640
ISO
IEA
Genome Projectnuclear outer membrane
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005886
IDA
ISO
IEA
Genome Projectplasma membrane
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IDA
ISO
IEA
Genome Projectintegral component of membrane
GO:0016363
ISO
IEA
Genome Projectnuclear matrix
GO:0030141
ISO
IEA
Genome Projectsecretory granule

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000832GPCR, family 2, secretin-like
IPR001879GPCR, family 2, extracellular hormone receptor domain
IPR003288GPCR, family 2, growth hormone-releasing hormone receptor
IPR017981GPCR, family 2-like
IPR017983GPCR, family 2, secretin-like, conserved site

No MapMan annotations defined for this gene.