Gene: ENSMUSG00000004264 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000004264
Transcript Identifier
ENSMUST00000004375
Gene Type
Coding gene
Location
6 : 124712437-124716633 : positive

Family Information

Homologous gene family
HOM03P000440
(104 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000553
(47 genes in 38 species)
specific family

Descriptions

gene_descr
prohibitin 2

Identifiers

Type Value
UniprotO35129
UniprotQ3V235
MGI102520

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000060
ISO
Genome Projectprotein import into nucleus, translocation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007005
ISO
Genome Projectmitochondrion organization
GO:0007062
ISO
Genome Projectsister chromatid cohesion
GO:0031536
ISO
Genome Projectpositive regulation of exit from mitosis
GO:0033147
IMP, IGI
Genome Projectnegative regulation of intracellular estrogen receptor signaling pathway
GO:0033600
IMP
Genome Projectnegative regulation of mammary gland epithelial cell proliferation
GO:0043066
ISO
Genome Projectnegative regulation of apoptotic process
GO:0043433
ISO
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892
IDA
ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0050821
ISO
Genome Projectprotein stabilization
GO:0051091
ISO
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0060744
IMP
Genome Projectmammary gland branching involved in thelarche
GO:0060749
IMP
Genome Projectmammary gland alveolus development
GO:0060762
IMP
Genome Projectregulation of branching involved in mammary gland duct morphogenesis
GO:0070374
ISO
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:1902808
ISO
Genome Projectpositive regulation of cell cycle G1/S phase transition

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
ISO
Genome Projectprotein C-terminus binding
GO:0033218
ISO
Genome Projectamide binding
GO:0047485
ISO
Genome Projectprotein N-terminus binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005739
IDA
ISO
IEA
Genome Projectmitochondrion
GO:0005741
ISO
Genome Projectmitochondrial outer membrane
GO:0005743
IDA
IEA
Genome Projectmitochondrial inner membrane
GO:0009986
IDA
ISO
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016363
ISS, ISO
IEA
Genome Projectnuclear matrix
GO:0043234
ISS, ISO
IEA
Genome Projectprotein complex
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0071944
ISO
Genome Projectcell periphery

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000163Prohibitin
IPR001107Band 7 domain

No MapMan annotations defined for this gene.