Gene: ENSMUSG00000004231 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000004231
Transcript Identifier
ENSMUST00000004340
Gene Type
Coding gene
Location
19 : 44757394-44836027 : positive

Family Information

Homologous gene family
HOM03P000330
(126 genes in 5 species)
specific family
Orthologous gene family
ORTHO03P070878
(2 genes in 2 species)
specific family

Descriptions

gene_descr
paired box 2

Identifiers

Type Value
UniprotG3X8Q7
MGI97486

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IGI
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001655
IMP
Genome Projecturogenital system development
GO:0001656
IMP, IGI
Genome Projectmetanephros development
GO:0001657
IGI
Genome Projectureteric bud development
GO:0001658
IMP, IGI
Genome Projectbranching involved in ureteric bud morphogenesis
GO:0001709
IMP
Genome Projectcell fate determination
GO:0001822
IMP, IGI
Genome Projectkidney development
GO:0001823
IMP
Genome Projectmesonephros development
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0035566
ISO
Genome Projectregulation of metanephros size
GO:0042472
IMP, IGI
Genome Projectinner ear morphogenesis
GO:0043010
IMP
Genome Projectcamera-type eye development
GO:0043066
ISO
Genome Projectnegative regulation of apoptotic process
GO:0043067
IGI
Genome Projectregulation of programmed cell death
GO:0043069
IMP
Genome Projectnegative regulation of programmed cell death
GO:0043154
ISO
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045892
ISO
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
ISO
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045918
ISO
Genome Projectnegative regulation of cytolysis
GO:0045944
IDA
ISO
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0050679
ISO
Genome Projectpositive regulation of epithelial cell proliferation
GO:0060231
IMP
Genome Projectmesenchymal to epithelial transition
GO:0072001
IGI
Genome Projectrenal system development
GO:0090103
IMP
Genome Projectcochlea morphogenesis
GO:2000378
ISO
Genome Projectnegative regulation of reactive oxygen species metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000987
ISO
Genome Projectcore promoter proximal region sequence-specific DNA binding
GO:0003677
IDA
ISO
IEA
Genome ProjectDNA binding
GO:0003700
TAS
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
ISO
Genome Projecttranscription factor binding
GO:0044212
ISO
Genome Projecttranscription regulatory region DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005667
TAS
Genome Projecttranscription factor complex
GO:0005815
ISO
Genome Projectmicrotubule organizing center
GO:0034451
ISO
Genome Projectcentriolar satellite

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001523Paired domain
IPR009057Homeodomain-like
IPR011991Winged helix-turn-helix DNA-binding domain
IPR022130Paired-box protein 2 C-terminal

No MapMan annotations defined for this gene.