Gene: ENSMUSG00000004054 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000004054
Transcript Identifier
ENSMUST00000004156
Gene Type
Coding gene
Location
19 : 5690247-5702344 : positive

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P011954
(7 genes in 3 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
mitogen-activated protein kinase kinase kinase 11

Identifiers

Type Value
UniprotQ80XI6
MGI1346880

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
ISO
IEA
Genome Projectactivation of MAPK activity
GO:0006468
ISO
IEA
Genome Projectprotein phosphorylation
GO:0007017
ISO
IEA
Genome Projectmicrotubule-based process
GO:0007254
IEA
Genome ProjectJNK cascade
GO:0007256
IEA
Genome Projectactivation of JNKK activity
GO:0007257
ISO
IEA
Genome Projectactivation of JUN kinase activity
GO:0008219
IEA
Genome Projectcell death
GO:0008283
ISO
IEA
Genome Projectcell proliferation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018108
IEA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043507
ISO
IEA
Genome Projectpositive regulation of JUN kinase activity
GO:0043525
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0046330
ISO
IEA
Genome Projectpositive regulation of JNK cascade
GO:0046777
ISO
IEA
Genome Projectprotein autophosphorylation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004706
IEA
Genome ProjectJUN kinase kinase kinase activity
GO:0004709
IEA
Genome ProjectMAP kinase kinase kinase activity
GO:0004713
IEA
Genome Projectprotein tyrosine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0031434
IEA
Genome Projectmitogen-activated protein kinase kinase binding
GO:0031435
ISO
IEA
Genome Projectmitogen-activated protein kinase kinase kinase binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0042803
ISO
IEA
Genome Projectprotein homodimerization activity
GO:0048365
IEA
Genome ProjectRac GTPase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005813
ISO
IEA
Genome Projectcentrosome
GO:0005815
IEA
Genome Projectmicrotubule organizing center
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005874
ISO
IEA
Genome Projectmicrotubule
GO:0016020
ISO
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001452SH3 domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site
IPR020635Tyrosine-protein kinase, catalytic domain

No MapMan annotations defined for this gene.