Gene: ENSMUSG00000003534 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000003534
Transcript Identifier
ENSMUST00000003628
Gene Type
Coding gene
Location
17 : 35682378-35693875 : negative

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P008919
(9 genes in 4 species)
specific family

Descriptions

gene_descr
discoidin domain receptor family, member 1

Identifiers

Type Value
UniprotQ03146
MGI99216

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001558
IMP
Genome Projectregulation of cell growth
GO:0001952
IMP
Genome Projectregulation of cell-matrix adhesion
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007169
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007565
IEA
Genome Projectfemale pregnancy
GO:0007566
IMP
Genome Projectembryo implantation
GO:0007595
IEA
Genome Projectlactation
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0010715
IMP
ISO
IEA
Genome Projectregulation of extracellular matrix disassembly
GO:0014909
IMP
ISO
IEA
Genome Projectsmooth muscle cell migration
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018108
IDA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0031100
IEA
Genome Projectorgan regeneration
GO:0038063
IMP
ISO
IEA
Genome Projectcollagen-activated tyrosine kinase receptor signaling pathway
GO:0038083
ISS, ISO
IEA
Genome Projectpeptidyl-tyrosine autophosphorylation
GO:0043583
IMP
Genome Projectear development
GO:0043588
IEA
Genome Projectskin development
GO:0044319
IMP
ISO
IEA
Genome Projectwound healing, spreading of cells
GO:0046777
ISO
IEA
Genome Projectprotein autophosphorylation
GO:0060444
IMP
Genome Projectbranching involved in mammary gland duct morphogenesis
GO:0060749
IMP
Genome Projectmammary gland alveolus development
GO:0061302
IMP
ISO
IEA
Genome Projectsmooth muscle cell-matrix adhesion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004714
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase activity
GO:0005518
IMP
ISO
IEA
Genome Projectcollagen binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0038062
ISS, ISO
IEA
Genome Projectprotein tyrosine kinase collagen receptor activity
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0005887
IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016323
IEA
Genome Projectbasolateral plasma membrane
GO:0043235
ISO
IEA
Genome Projectreceptor complex
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000421Coagulation factor 5/8 C-terminal domain
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002011Tyrosine-protein kinase, receptor class II, conserved site
IPR008266Tyrosine-protein kinase, active site
IPR008979Galactose-binding domain-like
IPR011009Protein kinase-like domain
IPR020635Tyrosine-protein kinase, catalytic domain
IPR029553Discoidin domain-containing receptor

No MapMan annotations defined for this gene.