Gene: ENSMUSG00000003518 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000003518
Transcript Identifier
ENSMUST00000107173
Gene Type
Coding gene
Location
11 : 101974734-101986926 : negative

Family Information

Homologous gene family
HOM03P000093
(285 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P018258
(5 genes in 3 species)
specific family

Descriptions

gene_descr
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)

Identifiers

Type Value
UniprotB1AQF4
MGI1919599

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000188
ISO
Genome Projectinactivation of MAPK activity
GO:0006470
IDA
IEA
Genome Projectprotein dephosphorylation
GO:0016311
IEA
Genome Projectdephosphorylation
GO:0035335
ISO
Genome Projectpeptidyl-tyrosine dephosphorylation
GO:0043409
ISO
Genome Projectnegative regulation of MAPK cascade
GO:0045931
ISO, IBA
Genome Projectpositive regulation of mitotic cell cycle
GO:0046329
ISO, IBA
Genome Projectnegative regulation of JNK cascade
GO:0050860
ISO, IBA
Genome Projectnegative regulation of T cell receptor signaling pathway
GO:0050868
ISO, IBA
Genome Projectnegative regulation of T cell activation
GO:0070373
ISO, IBA
Genome Projectnegative regulation of ERK1 and ERK2 cascade

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004721
IDA
Genome Projectphosphoprotein phosphatase activity
GO:0004725
ISO
IEA
Genome Projectprotein tyrosine phosphatase activity
GO:0008138
IDA
ISO
IEA
Genome Projectprotein tyrosine/serine/threonine phosphatase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016791
IEA
Genome Projectphosphatase activity
GO:0019901
ISO
Genome Projectprotein kinase binding
GO:0033549
ISO, IBA
Genome ProjectMAP kinase phosphatase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001772
ISO
Genome Projectimmunological synapse
GO:0005634
ISO
Genome Projectnucleus
GO:0005654
ISO
Genome Projectnucleoplasm
GO:0005737
ISO
Genome Projectcytoplasm
GO:0005829
ISO, IBA
Genome Projectcytosol
GO:0070062
ISO
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000340Dual specificity phosphatase, catalytic domain
IPR000387Tyrosine specific protein phosphatases domain
IPR016130Protein-tyrosine phosphatase, active site
IPR020405Atypical dual specificity phosphatase, subfamily A
IPR020417Atypical dual specificity phosphatase
IPR020422Dual specificity protein phosphatase domain
IPR024950Dual specificity phosphatase
IPR029021Protein-tyrosine phosphatase-like

No MapMan annotations defined for this gene.