Gene: ENSMUSG00000003031 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000003031
Transcript Identifier
ENSMUST00000003115
Gene Type
Coding gene
Location
6 : 134920920-134922074 : positive

Family Information

Homologous gene family
HOM03P029825
(3 genes in 2 species)
specific family

Descriptions

gene_descr
cyclin-dependent kinase inhibitor 1B

Identifiers

Type Value
UniprotP46414
MGI104565

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000082
IDA
ISO
IEA
Genome ProjectG1/S transition of mitotic cell cycle
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0006813
IGI
Genome Projectpotassium ion transport
GO:0006919
ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007049
IEA
Genome Projectcell cycle
GO:0007050
IDA
ISO
IEA
Genome Projectcell cycle arrest
GO:0007219
IDA
Genome ProjectNotch signaling pathway
GO:0007605
IMP
Genome Projectsensory perception of sound
GO:0008219
IEA
Genome Projectcell death
GO:0008284
IMP
Genome Projectpositive regulation of cell proliferation
GO:0008285
IMP
ISO
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009749
IEA
Genome Projectresponse to glucose
GO:0010942
ISO
IEA
Genome Projectpositive regulation of cell death
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0030308
ISO
IEA
Genome Projectnegative regulation of cell growth
GO:0031116
IGI
Genome Projectpositive regulation of microtubule polymerization
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0033673
ISO
IEA
Genome Projectnegative regulation of kinase activity
GO:0042127
IEA
Genome Projectregulation of cell proliferation
GO:0042326
ISO
IEA
Genome Projectnegative regulation of phosphorylation
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043066
IMP
Genome Projectnegative regulation of apoptotic process
GO:0043200
IEA
Genome Projectresponse to amino acid
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0045732
IEA
Genome Projectpositive regulation of protein catabolic process
GO:0045736
IDA
Genome Projectnegative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892
ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045930
ISO
IEA
Genome Projectnegative regulation of mitotic cell cycle
GO:0046686
IEA
Genome Projectresponse to cadmium ion
GO:0048102
ISO
IEA
Genome Projectautophagic cell death
GO:0048839
IMP
Genome Projectinner ear development
GO:0050680
IMP
Genome Projectnegative regulation of epithelial cell proliferation
GO:0051271
IDA
Genome Projectnegative regulation of cellular component movement
GO:0060770
IMP
Genome Projectnegative regulation of epithelial cell proliferation involved in prostate gland development
GO:0071236
IDA
Genome Projectcellular response to antibiotic
GO:0071285
ISO
IEA
Genome Projectcellular response to lithium ion
GO:0071407
IDA
Genome Projectcellular response to organic cyclic compound
GO:0071850
ISO
IEA
Genome Projectmitotic cell cycle arrest

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004860
IEA
Genome Projectprotein kinase inhibitor activity
GO:0004861
IDA
IEA
Genome Projectcyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008656
ISO
IEA
Genome Projectcysteine-type endopeptidase activator activity involved in apoptotic process
GO:0019903
ISO
IEA
Genome Projectprotein phosphatase binding
GO:0030544
IEA
Genome ProjectHsp70 protein binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0051087
IEA
Genome Projectchaperone binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0031464
IEA
Genome ProjectCul4A-RING E3 ubiquitin ligase complex
GO:0043234
IEA
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003175Cyclin-dependent kinase inhibitor
IPR029843Cyclin-dependent kinase inhibitor 1B

No MapMan annotations defined for this gene.