Gene: ENSMUSG00000002413 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000002413
Transcript Identifier
ENSMUST00000002487
Gene Type
Coding gene
Location
6 : 39610382-39725295 : negative

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P012430
(7 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
Braf transforming gene

Identifiers

Type Value
UniprotP28028
MGI88190

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000165
IEA
Genome ProjectMAPK cascade
GO:0000186
IEA
Genome Projectactivation of MAPKK activity
GO:0002318
IMP
Genome Projectmyeloid progenitor cell differentiation
GO:0006468
IDA
ISO
IEA
Genome Projectprotein phosphorylation
GO:0007165
IEA
Genome Projectsignal transduction
GO:0008542
IMP
Genome Projectvisual learning
GO:0010628
IGI
ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0010764
IMP
Genome Projectnegative regulation of fibroblast migration
GO:0015758
ISO
IEA
Genome Projectglucose transport
GO:0016310
IEA
Genome Projectphosphorylation
GO:0030154
IGI
Genome Projectcell differentiation
GO:0033138
ISO
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0035019
IGI
Genome Projectsomatic stem cell population maintenance
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0035690
IDA
Genome Projectcellular response to drug
GO:0042127
IGI
Genome Projectregulation of cell proliferation
GO:0043066
ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043367
IMP
Genome ProjectCD4-positive, alpha-beta T cell differentiation
GO:0043368
IMP
Genome Projectpositive T cell selection
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0043524
IMP
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0046632
IMP
Genome Projectalpha-beta T cell differentiation
GO:0048679
IGI
Genome Projectregulation of axon regeneration
GO:0048680
IDA
Genome Projectpositive regulation of axon regeneration
GO:0050772
IMP, IGI
Genome Projectpositive regulation of axonogenesis
GO:0051291
IEA
Genome Projectprotein heterooligomerization
GO:0051496
IMP, IGI
Genome Projectpositive regulation of stress fiber assembly
GO:0051591
IEA
Genome Projectresponse to cAMP
GO:0060291
IMP
Genome Projectlong-term synaptic potentiation
GO:0060323
IMP
Genome Projecthead morphogenesis
GO:0070374
IDA, IMP
ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071277
ISO
IEA
Genome Projectcellular response to calcium ion
GO:0090150
ISO
IEA
Genome Projectestablishment of protein localization to membrane
GO:1900026
IMP
Genome Projectpositive regulation of substrate adhesion-dependent cell spreading
GO:2000301
IMP
Genome Projectnegative regulation of synaptic vesicle exocytosis
GO:2000352
IMP
Genome Projectnegative regulation of endothelial cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IDA
ISO
IEA
Genome Projectprotein kinase activity
GO:0004674
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004709
IEA
Genome ProjectMAP kinase kinase kinase activity
GO:0005057
IEA
Genome Projectreceptor signaling protein activity
GO:0005509
ISO
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0031434
IEA
Genome Projectmitogen-activated protein kinase kinase binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IDA
Genome Projectmitochondrion
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0043005
IDA
IEA
Genome Projectneuron projection
GO:0044297
IDA
Genome Projectcell body

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR003116Raf-like Ras-binding
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site
IPR020454Diacylglycerol/phorbol-ester binding
IPR029071Ubiquitin-related domain

No MapMan annotations defined for this gene.