Gene: ENSMUSG00000002108 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000002108
Transcript Identifier
ENSMUST00000111354
Gene Type
Coding gene
Location
2 : 91184336-91193659 : negative

Family Information

Homologous gene family
HOM03P000128
(228 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P024867
(4 genes in 3 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
nuclear receptor subfamily 1, group H, member 3

Identifiers

Type Value
UniprotQ9Z0Y9
UniprotQ91X41
MGI1352462

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IDA
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0008286
IEA
Genome Projectinsulin receptor signaling pathway
GO:0010867
ISO
Genome Projectpositive regulation of triglyceride biosynthetic process
GO:0010870
ISO
Genome Projectpositive regulation of receptor biosynthetic process
GO:0010875
IDA
ISO
Genome Projectpositive regulation of cholesterol efflux
GO:0010887
IGI
ISO
Genome Projectnegative regulation of cholesterol storage
GO:0030522
IDA
Genome Projectintracellular receptor signaling pathway
GO:0032270
ISO
Genome Projectpositive regulation of cellular protein metabolic process
GO:0032369
ISO
Genome Projectnegative regulation of lipid transport
GO:0032376
ISO
Genome Projectpositive regulation of cholesterol transport
GO:0032570
ISO
Genome Projectresponse to progesterone
GO:0034145
ISO
Genome Projectpositive regulation of toll-like receptor 4 signaling pathway
GO:0043277
ISO
Genome Projectapoptotic cell clearance
GO:0043401
IEA
Genome Projectsteroid hormone mediated signaling pathway
GO:0044255
IDA
Genome Projectcellular lipid metabolic process
GO:0045723
ISO
Genome Projectpositive regulation of fatty acid biosynthetic process
GO:0045892
IMP
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IMP
ISO
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
ISO
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048550
ISO
Genome Projectnegative regulation of pinocytosis
GO:0051006
ISO
Genome Projectpositive regulation of lipoprotein lipase activity
GO:0071222
IDA
ISO
Genome Projectcellular response to lipopolysaccharide
GO:2000189
ISO
Genome Projectpositive regulation of cholesterol homeostasis
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006633
TAS
Genome Projectfatty acid biosynthetic process
GO:0042632
IGI
Genome Projectcholesterol homeostasis
GO:0043031
IDA
Genome Projectnegative regulation of macrophage activation
GO:0045861
IMP
Genome Projectnegative regulation of proteolysis
GO:0050728
IDA
Genome Projectnegative regulation of inflammatory response
GO:0055088
IMP, IGI
Genome Projectlipid homeostasis
GO:0055092
IMP
Genome Projectsterol homeostasis
GO:0070328
IMP, IGI
Genome Projecttriglyceride homeostasis
GO:0090188
IMP
Genome Projectnegative regulation of pancreatic juice secretion
GO:0090341
IMP
Genome Projectnegative regulation of secretion of lysosomal enzymes
GO:2000188
IMP
Genome Projectregulation of cholesterol homeostasis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003700
IDA
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003707
IEA
Genome Projectsteroid hormone receptor activity
GO:0004879
IDA
Genome ProjectRNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0032810
ISO
Genome Projectsterol response element binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
IDA
ISO
Genome Projecttranscription regulatory region DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046965
IEA
Genome Projectretinoid X receptor binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity
GO:0000978
IDA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
ISO
Genome Projectnuclear chromatin
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0043235
ISO
Genome Projectreceptor complex
GO:0090575
IDA
ISO
Genome ProjectRNA polymerase II transcription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000536Nuclear hormone receptor, ligand-binding domain
IPR001628Zinc finger, nuclear hormone receptor-type
IPR001723Nuclear hormone receptor
IPR013088Zinc finger, NHR/GATA-type
IPR023257Liver X receptor

No MapMan annotations defined for this gene.