Gene: ENSMUSG00000002028 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000002028
Transcript Identifier
ENSMUST00000114689
Gene Type
Coding gene
Location
9 : 44807902-44881274 : negative

Family Information

Homologous gene family
HOM03P000090
(299 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P065978
(2 genes in 2 species)
specific family

Descriptions

gene_descr
lysine (K)-specific methyltransferase 2A

Identifiers

Type Value
UniprotP55200
MGI96995

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006306
IMP
Genome ProjectDNA methylation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006461
ISO
IEA
Genome Projectprotein complex assembly
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0008542
IMP
Genome Projectvisual learning
GO:0009416
IMP
Genome Projectresponse to light stimulus
GO:0009952
IMP, IGI
Genome Projectanterior/posterior pattern specification
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0016568
IEA
Genome Projectchromatin modification
GO:0018026
IMP
Genome Projectpeptidyl-lysine monomethylation
GO:0032259
IEA
Genome Projectmethylation
GO:0032411
ISO
IEA
Genome Projectpositive regulation of transporter activity
GO:0032922
IMP
Genome Projectcircadian regulation of gene expression
GO:0035162
IMP
Genome Projectembryonic hemopoiesis
GO:0035640
IMP
Genome Projectexploration behavior
GO:0035864
IEA
Genome Projectresponse to potassium ion
GO:0043984
ISS, ISO
IEA
Genome Projecthistone H4-K16 acetylation
GO:0044648
IMP
Genome Projecthistone H3-K4 dimethylation
GO:0045893
IDA
ISS, ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IGI
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048172
IMP
Genome Projectregulation of short-term neuronal synaptic plasticity
GO:0048511
IEA
Genome Projectrhythmic process
GO:0050890
IMP
Genome Projectcognition
GO:0051568
ISS, ISO
IEA
Genome Projecthistone H3-K4 methylation
GO:0051569
IMP
Genome Projectregulation of histone H3-K4 methylation
GO:0051571
IMP
Genome Projectpositive regulation of histone H3-K4 methylation
GO:0051899
IEA
Genome Projectmembrane depolarization
GO:0060216
IMP
Genome Projectdefinitive hemopoiesis
GO:0071440
IMP
Genome Projectregulation of histone H3-K14 acetylation
GO:0080182
IMP
ISO
IEA
Genome Projecthistone H3-K4 trimethylation
GO:1901674
IMP
Genome Projectregulation of histone H3-K27 acetylation
GO:2000615
IMP
Genome Projectregulation of histone H3-K9 acetylation
GO:2001040
ISO
IEA
Genome Projectpositive regulation of cellular response to drug

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001046
IDA
Genome Projectcore promoter sequence-specific DNA binding
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003682
IDA
Genome Projectchromatin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008168
IEA
Genome Projectmethyltransferase activity
GO:0008270
ISS, ISO
IEA
Genome Projectzinc ion binding
GO:0016740
IEA
Genome Projecttransferase activity
GO:0018024
IEA
Genome Projecthistone-lysine N-methyltransferase activity
GO:0042800
ISS, ISO
IEA
Genome Projecthistone methyltransferase activity (H3-K4 specific)
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0042803
ISO
IEA
Genome Projectprotein homodimerization activity
GO:0044212
ISO
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0045322
ISS, ISO
IEA
Genome Projectunmethylated CpG binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0070577
ISS, ISO
IEA
Genome Projectlysine-acetylated histone binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0035097
ISS, ISO
IEA
Genome Projecthistone methyltransferase complex
GO:0071339
ISS, ISO
IEA
Genome ProjectMLL1 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001214SET domain
IPR001487Bromodomain
IPR001965Zinc finger, PHD-type
IPR002857Zinc finger, CXXC-type
IPR003616Post-SET domain
IPR003888FY-rich, N-terminal
IPR003889FY-rich, C-terminal
IPR011011Zinc finger, FYVE/PHD-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR016569Methyltransferase, trithorax
IPR017956AT hook, DNA-binding motif
IPR019787Zinc finger, PHD-finger

No MapMan annotations defined for this gene.