Gene: ENSMUSG00000001729 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000001729
Transcript Identifier
ENSMUST00000001780
Gene Type
Coding gene
Location
12 : 112654698-112671561 : negative

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P010242
(8 genes in 4 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
thymoma viral proto-oncogene 1

Identifiers

Type Value
UniprotP31750
MGI87986

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000060
ISO
IEA
Genome Projectprotein import into nucleus, translocation
GO:0001649
IGI
Genome Projectosteoblast differentiation
GO:0001893
IMP
Genome Projectmaternal placenta development
GO:0001934
ISO
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0001938
ISS, ISO
IEA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0005975
IEA
Genome Projectcarbohydrate metabolic process
GO:0005977
IMP
IEA
Genome Projectglycogen metabolic process
GO:0005978
IEA
Genome Projectglycogen biosynthetic process
GO:0005979
ISO
IEA
Genome Projectregulation of glycogen biosynthetic process
GO:0006006
IMP
IEA
Genome Projectglucose metabolic process
GO:0006412
IEA
Genome Projecttranslation
GO:0006417
IEA
Genome Projectregulation of translation
GO:0006468
IDA
ISO
IEA
Genome Projectprotein phosphorylation
GO:0006469
ISO
IEA
Genome Projectnegative regulation of protein kinase activity
GO:0006810
IEA
Genome Projecttransport
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006924
ISO
IEA
Genome Projectactivation-induced cell death of T cells
GO:0006954
IDA
Genome Projectinflammatory response
GO:0006979
ISS
Genome Projectresponse to oxidative stress
GO:0007010
TAS
Genome Projectcytoskeleton organization
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007281
IDA
Genome Projectgerm cell development
GO:0007399
IEA
Genome Projectnervous system development
GO:0007568
IEA
Genome Projectaging
GO:0008286
IMP
ISS, ISO
IEA
Genome Projectinsulin receptor signaling pathway
GO:0008637
IDA
Genome Projectapoptotic mitochondrial changes
GO:0008643
IEA
Genome Projectcarbohydrate transport
GO:0009725
IDA
Genome Projectresponse to hormone
GO:0010507
ISO
IEA
Genome Projectnegative regulation of autophagy
GO:0010629
IDA
Genome Projectnegative regulation of gene expression
GO:0010748
ISO
IEA
Genome Projectnegative regulation of plasma membrane long-chain fatty acid transport
GO:0010763
IMP
Genome Projectpositive regulation of fibroblast migration
GO:0010765
IDA, IMP
ISO
IEA
Genome Projectpositive regulation of sodium ion transport
GO:0010907
ISO
IEA
Genome Projectpositive regulation of glucose metabolic process
GO:0010951
ISO
IEA
Genome Projectnegative regulation of endopeptidase activity
GO:0010975
IDA
Genome Projectregulation of neuron projection development
GO:0015758
IMP
Genome Projectglucose transport
GO:0016310
ISO
IEA
Genome Projectphosphorylation
GO:0016567
IDA
Genome Projectprotein ubiquitination
GO:0018105
IDA
ISO
IEA
Genome Projectpeptidyl-serine phosphorylation
GO:0030030
ISO
IEA
Genome Projectcell projection organization
GO:0030163
IDA
Genome Projectprotein catabolic process
GO:0030212
IEA
Genome Projecthyaluronan metabolic process
GO:0030307
ISO
IEA
Genome Projectpositive regulation of cell growth
GO:0030334
ISS, ISO
IEA
Genome Projectregulation of cell migration
GO:0031018
TAS
Genome Projectendocrine pancreas development
GO:0031641
IMP
Genome Projectregulation of myelination
GO:0031659
ISO
IEA
Genome Projectpositive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
GO:0031663
IDA
Genome Projectlipopolysaccharide-mediated signaling pathway
GO:0031999
ISO
IEA
Genome Projectnegative regulation of fatty acid beta-oxidation
GO:0032094
IDA
Genome Projectresponse to food
GO:0032270
IEA
Genome Projectpositive regulation of cellular protein metabolic process
GO:0032287
IMP
Genome Projectperipheral nervous system myelin maintenance
GO:0032436
IMP
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032869
IDA, IMP
ISO
IEA
Genome Projectcellular response to insulin stimulus
GO:0032880
IDA
ISO
IEA
Genome Projectregulation of protein localization
GO:0033138
ISO
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0034405
ISO
IEA
Genome Projectresponse to fluid shear stress
GO:0035556
ISO
IEA
Genome Projectintracellular signal transduction
GO:0035924
IDA
Genome Projectcellular response to vascular endothelial growth factor stimulus
GO:0036294
IDA
Genome Projectcellular response to decreased oxygen levels
GO:0042593
IMP
Genome Projectglucose homeostasis
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043066
IMP
ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043154
IDA
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043491
IGI
Genome Projectprotein kinase B signaling
GO:0043536
ISO
IEA
Genome Projectpositive regulation of blood vessel endothelial cell migration
GO:0045429
ISO
IEA
Genome Projectpositive regulation of nitric oxide biosynthetic process
GO:0045600
ISO
IEA
Genome Projectpositive regulation of fat cell differentiation
GO:0045725
ISO
IEA
Genome Projectpositive regulation of glycogen biosynthetic process
GO:0045792
ISO
IEA
Genome Projectnegative regulation of cell size
GO:0045861
ISO
IEA
Genome Projectnegative regulation of proteolysis
GO:0045907
IEA
Genome Projectpositive regulation of vasoconstriction
GO:0045944
IGI
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046326
ISO
IEA
Genome Projectpositive regulation of glucose import
GO:0046329
IEA
Genome Projectnegative regulation of JNK cascade
GO:0046889
ISO
IEA
Genome Projectpositive regulation of lipid biosynthetic process
GO:0048009
ISS, ISO
IEA
Genome Projectinsulin-like growth factor receptor signaling pathway
GO:0051000
ISO
IEA
Genome Projectpositive regulation of nitric-oxide synthase activity
GO:0051091
ISO
IEA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051146
IGI
Genome Projectstriated muscle cell differentiation
GO:0060416
ISS
Genome Projectresponse to growth hormone
GO:0060709
IMP
Genome Projectglycogen cell differentiation involved in embryonic placenta development
GO:0060716
IMP
Genome Projectlabyrinthine layer blood vessel development
GO:0070141
ISO
IEA
Genome Projectresponse to UV-A
GO:0071260
IEA
Genome Projectcellular response to mechanical stimulus
GO:0071363
IDA
Genome Projectcellular response to growth factor stimulus
GO:0071364
IDA
Genome Projectcellular response to epidermal growth factor stimulus
GO:0071380
IDA
Genome Projectcellular response to prostaglandin E stimulus
GO:0071407
IEA
Genome Projectcellular response to organic cyclic compound
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:0090004
ISO
IEA
Genome Projectpositive regulation of establishment of protein localization to plasma membrane
GO:0090201
IDA
Genome Projectnegative regulation of release of cytochrome c from mitochondria
GO:0097011
IDA
Genome Projectcellular response to granulocyte macrophage colony-stimulating factor stimulus
GO:0097194
IDA
Genome Projectexecution phase of apoptosis
GO:1901653
IDA
Genome Projectcellular response to peptide
GO:1990418
ISS
Genome Projectresponse to insulin-like growth factor stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
ISS, ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004712
ISO
IEA
Genome Projectprotein serine/threonine/tyrosine kinase activity
GO:0005080
IEA
Genome Projectprotein kinase C binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
ISO
IEA
Genome ProjectATP binding
GO:0005547
ISO
IEA
Genome Projectphosphatidylinositol-3,4,5-trisphosphate binding
GO:0016301
ISO
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019899
IEA
Genome Projectenzyme binding
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0030235
ISO
IEA
Genome Projectnitric-oxide synthase regulator activity
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0043325
ISO
IEA
Genome Projectphosphatidylinositol-3,4-bisphosphate binding
GO:0051721
IEA
Genome Projectprotein phosphatase 2A binding
GO:0071889
ISO
IEA
Genome Project14-3-3 protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
TAS, IEA
Genome Projectnucleoplasm
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005739
IDA
Genome Projectmitochondrion
GO:0005819
IDA
Genome Projectspindle
GO:0005829
ISO
TAS, IEA
Genome Projectcytosol
GO:0005886
IDA
ISO
TAS, IEA
Genome Projectplasma membrane
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0015630
ISO
IEA
Genome Projectmicrotubule cytoskeleton
GO:0016020
IEA
Genome Projectmembrane
GO:0036064
IDA
Genome Projectciliary basal body
GO:0043234
IDA
ISO
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR001849Pleckstrin homology domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR011993PH domain-like
IPR017441Protein kinase, ATP binding site
IPR017892Protein kinase, C-terminal

No MapMan annotations defined for this gene.