Gene: ENSMUSG00000001127 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000001127
Transcript Identifier
ENSMUST00000001155
Gene Type
Coding gene
Location
X : 20849987-20860113 : positive

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P012430
(7 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
v-raf murine sarcoma 3611 viral oncogene homolog

Identifiers

Type Value
UniprotP04627
MGI88065

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000165
IEA
Genome ProjectMAPK cascade
GO:0000186
IEA
Genome Projectactivation of MAPKK activity
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007165
IEA
Genome Projectsignal transduction
GO:0016310
IEA
Genome Projectphosphorylation
GO:0032006
ISS, ISO
Genome Projectregulation of TOR signaling
GO:0032434
ISS, ISO
Genome Projectregulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033138
ISO
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0043066
ISO
Genome Projectnegative regulation of apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004709
IEA
Genome ProjectMAP kinase kinase kinase activity
GO:0005057
IEA
Genome Projectreceptor signaling protein activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
Genome Projectmitochondrion
GO:0005829
IEA
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR003116Raf-like Ras-binding
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site
IPR020454Diacylglycerol/phorbol-ester binding
IPR029071Ubiquitin-related domain

No MapMan annotations defined for this gene.