Gene: ENSMUSG00000000982 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000000982
Transcript Identifier
ENSMUST00000001008
Gene Type
Coding gene
Location
11 : 83648253-83649277 : negative

Family Information

Homologous gene family
HOM03P003119
(31 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P031343
(3 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
chemokine (C-C motif) ligand 3

Identifiers

Type Value
UniprotP10855
UniprotQ5QNW0
MGI98260

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000165
ISS
Genome ProjectMAPK cascade
GO:0001649
ISS
Genome Projectosteoblast differentiation
GO:0001775
ISS
Genome Projectcell activation
GO:0002548
ISS
Genome Projectmonocyte chemotaxis
GO:0006468
ISS
Genome Projectprotein phosphorylation
GO:0006816
ISS
Genome Projectcalcium ion transport
GO:0006874
ISS
Genome Projectcellular calcium ion homeostasis
GO:0006887
ISS
Genome Projectexocytosis
GO:0006935
ISS
IEA
Genome Projectchemotaxis
GO:0006954
ISS
IEA
Genome Projectinflammatory response
GO:0006955
IEA
Genome Projectimmune response
GO:0007010
ISS
Genome Projectcytoskeleton organization
GO:0007204
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007267
ISS
Genome Projectcell-cell signaling
GO:0008360
IDA
Genome Projectregulation of cell shape
GO:0009636
ISS
Genome Projectresponse to toxic substance
GO:0010628
ISS
Genome Projectpositive regulation of gene expression
GO:0010629
ISS
Genome Projectnegative regulation of gene expression
GO:0010818
ISS
Genome ProjectT cell chemotaxis
GO:0014808
ISS
Genome Projectrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0019722
ISS
Genome Projectcalcium-mediated signaling
GO:0023052
ISS
Genome Projectsignaling
GO:0030335
ISS
Genome Projectpositive regulation of cell migration
GO:0030593
ISS
IEA
Genome Projectneutrophil chemotaxis
GO:0030595
IEA
Genome Projectleukocyte chemotaxis
GO:0031663
ISS
Genome Projectlipopolysaccharide-mediated signaling pathway
GO:0032760
IGI
Genome Projectpositive regulation of tumor necrosis factor production
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043085
ISS
Genome Projectpositive regulation of catalytic activity
GO:0043308
ISS
Genome Projecteosinophil degranulation
GO:0043491
ISS
Genome Projectprotein kinase B signaling
GO:0043525
IGI
Genome Projectpositive regulation of neuron apoptotic process
GO:0043615
IDA
Genome Projectastrocyte cell migration
GO:0043922
ISS
Genome Projectnegative regulation by host of viral transcription
GO:0045671
ISS
Genome Projectnegative regulation of osteoclast differentiation
GO:0045672
IEA
Genome Projectpositive regulation of osteoclast differentiation
GO:0045944
IMP
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048245
ISS
Genome Projecteosinophil chemotaxis
GO:0048246
IGI
Genome Projectmacrophage chemotaxis
GO:0048247
ISS
Genome Projectlymphocyte chemotaxis
GO:0050718
IGI
Genome Projectpositive regulation of interleukin-1 beta secretion
GO:0050729
IGI
Genome Projectpositive regulation of inflammatory response
GO:0050850
ISS
Genome Projectpositive regulation of calcium-mediated signaling
GO:0050918
ISS
Genome Projectpositive chemotaxis
GO:0051928
ISS
Genome Projectpositive regulation of calcium ion transport
GO:0051930
ISS
Genome Projectregulation of sensory perception of pain
GO:0070374
ISS
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070723
ISS
Genome Projectresponse to cholesterol
GO:0071407
ISS
Genome Projectcellular response to organic cyclic compound
GO:0071621
ISS
Genome Projectgranulocyte chemotaxis
GO:2000503
ISS
Genome Projectpositive regulation of natural killer cell chemotaxis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004672
ISS
Genome Projectprotein kinase activity
GO:0004698
ISS
Genome Projectcalcium-dependent protein kinase C activity
GO:0005125
IEA
Genome Projectcytokine activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008009
IDA
IEA
Genome Projectchemokine activity
GO:0016004
ISS
Genome Projectphospholipase activator activity
GO:0016301
ISS
Genome Projectkinase activity
GO:0042056
ISS
Genome Projectchemoattractant activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005622
ISS
Genome Projectintracellular
GO:0005737
ISS
Genome Projectcytoplasm
GO:0005829
ISS
IEA
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000827CC chemokine, conserved site
IPR001811Chemokine interleukin-8-like domain

No MapMan annotations defined for this gene.