Gene: ENSMUSG00000000889 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000000889
Transcript Identifier
ENSMUST00000000910
Gene Type
Coding gene
Location
2 : 27165516-27182800 : positive

Family Information

Homologous gene family
HOM03P004388
(22 genes in 9 species)
specific family
Orthologous gene family
ORTHO03P029387
(4 genes in 4 species)
specific family

Descriptions

gene_descr
dopamine beta hydroxylase

Identifiers

Type Value
UniprotQ64237
MGI94864

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001816
IMP
Genome Projectcytokine production
GO:0001974
IMP
Genome Projectblood vessel remodeling
GO:0001975
IMP
Genome Projectresponse to amphetamine
GO:0002443
IMP
Genome Projectleukocyte mediated immunity
GO:0007613
IMP
Genome Projectmemory
GO:0007626
IMP
Genome Projectlocomotory behavior
GO:0008306
IMP
Genome Projectassociative learning
GO:0008542
IMP
Genome Projectvisual learning
GO:0042127
IMP
Genome Projectregulation of cell proliferation
GO:0042309
IMP
Genome Projecthomoiothermy
GO:0042420
IMP
Genome Projectdopamine catabolic process
GO:0042421
IMP
IEA
Genome Projectnorepinephrine biosynthetic process
GO:0042423
IEA
Genome Projectcatecholamine biosynthetic process
GO:0042593
IMP
Genome Projectglucose homeostasis
GO:0042596
IMP
Genome Projectfear response
GO:0042711
IMP
Genome Projectmaternal behavior
GO:0045907
IMP
Genome Projectpositive regulation of vasoconstriction
GO:0048149
IMP
Genome Projectbehavioral response to ethanol
GO:0048265
IMP
Genome Projectresponse to pain
GO:0050900
IMP
Genome Projectleukocyte migration
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:2001236
IMP
Genome Projectregulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004497
IEA
Genome Projectmonooxygenase activity
GO:0004500
IEA
Genome Projectdopamine beta-monooxygenase activity
GO:0005507
IEA
Genome Projectcopper ion binding
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016715
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
GO:0031418
IEA
Genome ProjectL-ascorbic acid binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016023
IEA
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0030658
IEA
Genome Projecttransport vesicle membrane
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0034466
IEA
Genome Projectchromaffin granule lumen
GO:0042584
IEA
Genome Projectchromaffin granule membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000323Copper type II, ascorbate-dependent monooxygenase, N-terminal
IPR000945Dopamine beta-hydroxylase-related
IPR005018DOMON domain
IPR008977PHM/PNGase F domain
IPR014783Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site
IPR014784Copper type II, ascorbate-dependent monooxygenase-like, C-terminal
IPR020611Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site
IPR024548Copper type II ascorbate-dependent monooxygenase, C-terminal
IPR028460Tyramine beta-hydroxylase/Dopamine beta-hydroxylase

No MapMan annotations defined for this gene.