Gene: ENSMUSG00000000817 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000000817
Transcript Identifier
ENSMUST00000000834
Gene Type
Coding gene
Location
1 : 161781576-161788285 : negative

Family Information

Homologous gene family
HOM03P034777
(2 genes in 2 species)
specific family

Descriptions

gene_descr
Fas ligand (TNF superfamily, member 6)

Identifiers

Type Value
UniprotP41047
UniprotQ544E9
MGI99255

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
ISS, ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006919
ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006925
IEA
Genome Projectinflammatory cell apoptotic process
GO:0006955
IEA
Genome Projectimmune response
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008625
IDA
ISO
IEA
Genome Projectextrinsic apoptotic signaling pathway via death domain receptors
GO:0016525
ISO
IEA
Genome Projectnegative regulation of angiogenesis
GO:0030644
IEA
Genome Projectcellular chloride ion homeostasis
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0043065
ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043123
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043525
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0045742
IEA
Genome Projectpositive regulation of epidermal growth factor receptor signaling pathway
GO:0046666
IMP
Genome Projectretinal cell programmed cell death
GO:0048388
IEA
Genome Projectendosomal lumen acidification
GO:0070231
ISO
IEA
Genome ProjectT cell apoptotic process
GO:0070266
ISO
IEA
Genome Projectnecroptotic process
GO:0070848
IEA
Genome Projectresponse to growth factor
GO:0097190
IDA
ISO
IEA
Genome Projectapoptotic signaling pathway
GO:0097191
ISO
IEA
Genome Projectextrinsic apoptotic signaling pathway
GO:0097527
ISO
IEA
Genome Projectnecroptotic signaling pathway
GO:2000353
ISO
IEA
Genome Projectpositive regulation of endothelial cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005123
IEA
Genome Projectdeath receptor binding
GO:0005125
IEA
Genome Projectcytokine activity
GO:0005164
IEA
Genome Projecttumor necrosis factor receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005634
ISS, ISO
IEA
Genome Projectnucleus
GO:0005764
IEA
Genome Projectlysosome
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0005901
IEA
Genome Projectcaveola
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016023
IEA
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0043202
IEA
Genome Projectlysosomal lumen
GO:0045121
IEA
Genome Projectmembrane raft
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0060205
IEA
Genome Projectcytoplasmic membrane-bounded vesicle lumen
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR006052Tumour necrosis factor domain
IPR006053Tumour necrosis factor
IPR008983Tumour necrosis factor-like domain
IPR021184Tumour necrosis factor, conserved site
IPR028326Tumor necrosis factor ligand superfamily member 6

No MapMan annotations defined for this gene.