Gene: ENSMUSG00000000290 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000000290
Transcript Identifier
ENSMUST00000000299
Gene Type
Coding gene
Location
10 : 77541969-77565240 : positive

Family Information

Homologous gene family
HOM03P005934
(15 genes in 4 species)
specific family

Descriptions

gene_descr
integrin beta 2

Identifiers

Type Value
UniprotQ542I8
MGI96611

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007155
IMP, IGI
IEA
Genome Projectcell adhesion
GO:0007159
ISO
Genome Projectleukocyte cell-cell adhesion
GO:0007160
ISO
IEA
Genome Projectcell-matrix adhesion
GO:0007229
IDA
IEA
Genome Projectintegrin-mediated signaling pathway
GO:0016337
IGI
Genome Projectsingle organismal cell-cell adhesion
GO:0030593
IMP
ISO
Genome Projectneutrophil chemotaxis
GO:0034113
ISO
Genome Projectheterotypic cell-cell adhesion
GO:0043113
ISO
Genome Projectreceptor clustering
GO:0045123
IMP
Genome Projectcellular extravasation
GO:0050730
ISO
Genome Projectregulation of peptidyl-tyrosine phosphorylation
GO:0050798
IMP
Genome Projectactivated T cell proliferation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001948
ISO
Genome Projectglycoprotein binding
GO:0004872
IEA
Genome Projectreceptor activity
GO:0019901
ISO
Genome Projectprotein kinase binding
GO:0030369
ISO
Genome ProjectICAM-3 receptor activity
GO:0050839
ISO
Genome Projectcell adhesion molecule binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008305
IEA
Genome Projectintegrin complex
GO:0009986
IDA
ISO
Genome Projectcell surface
GO:0016020
IDA
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0034687
ISO
Genome Projectintegrin alphaL-beta2 complex
GO:0043235
ISO
Genome Projectreceptor complex
GO:0045121
IDA
Genome Projectmembrane raft
GO:0070062
ISO
Genome Projectextracellular exosome
GO:1903561
ISO
Genome Projectextracellular vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002035von Willebrand factor, type A
IPR002369Integrin beta subunit, N-terminal
IPR012896Integrin beta subunit, tail
IPR014836Integrin beta subunit, cytoplasmic domain
IPR015439Integrin beta-2 subunit
IPR015812Integrin beta subunit
IPR016201Plexin-like fold

No MapMan annotations defined for this gene.