Gene: ENSMUSG00000000215 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000000215
Transcript Identifier
ENSMUST00000105932
Gene Type
Coding gene
Location
7 : 142678713-142679533 : negative

Family Information

Homologous gene family
HOM03P022471
(4 genes in 2 species)
specific family

Descriptions

gene_descr
insulin II

Identifiers

Type Value
UniprotP01326
UniprotQ5EEX1
MGI96573

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000165
ISO
Genome ProjectMAPK cascade
GO:0000187
IDA
Genome Projectactivation of MAPK activity
GO:0002674
ISO
Genome Projectnegative regulation of acute inflammatory response
GO:0005975
IEA
Genome Projectcarbohydrate metabolic process
GO:0006006
IMP
IEA
Genome Projectglucose metabolic process
GO:0006521
ISO
Genome Projectregulation of cellular amino acid metabolic process
GO:0006953
ISO
Genome Projectacute-phase response
GO:0006983
IMP
Genome ProjectER overload response
GO:0007186
ISO
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007520
IGI
Genome Projectmyoblast fusion
GO:0008284
ISO
Genome Projectpositive regulation of cell proliferation
GO:0008286
IDA
ISO
Genome Projectinsulin receptor signaling pathway
GO:0010468
IDA
Genome Projectregulation of gene expression
GO:0014068
ISO
Genome Projectpositive regulation of phosphatidylinositol 3-kinase signaling
GO:0014902
IGI
Genome Projectmyotube differentiation
GO:0015758
ISO
TAS
Genome Projectglucose transport
GO:0016042
IDA
Genome Projectlipid catabolic process
GO:0022898
ISO
Genome Projectregulation of transmembrane transporter activity
GO:0032148
ISO
Genome Projectactivation of protein kinase B activity
GO:0032270
ISO
Genome Projectpositive regulation of cellular protein metabolic process
GO:0032460
ISO
Genome Projectnegative regulation of protein oligomerization
GO:0032880
ISO
Genome Projectregulation of protein localization
GO:0033861
ISO
Genome Projectnegative regulation of NAD(P)H oxidase activity
GO:0042060
ISO
Genome Projectwound healing
GO:0042177
ISO
Genome Projectnegative regulation of protein catabolic process
GO:0042325
IDA
Genome Projectregulation of phosphorylation
GO:0042593
ISO
Genome Projectglucose homeostasis
GO:0043393
IDA
Genome Projectregulation of protein binding
GO:0043410
ISO
Genome Projectpositive regulation of MAPK cascade
GO:0043552
IDA
Genome Projectpositive regulation of phosphatidylinositol 3-kinase activity
GO:0045725
ISO
Genome Projectpositive regulation of glycogen biosynthetic process
GO:0045740
ISO
Genome Projectpositive regulation of DNA replication
GO:0045818
ISO
Genome Projectnegative regulation of glycogen catabolic process
GO:0045821
ISO
Genome Projectpositive regulation of glycolytic process
GO:0045840
ISO
Genome Projectpositive regulation of mitotic nuclear division
GO:0045861
ISO
Genome Projectnegative regulation of proteolysis
GO:0045922
ISO
Genome Projectnegative regulation of fatty acid metabolic process
GO:0046326
ISO
Genome Projectpositive regulation of glucose import
GO:0046628
ISO
Genome Projectpositive regulation of insulin receptor signaling pathway
GO:0046631
ISO
Genome Projectalpha-beta T cell activation
GO:0050708
ISO
Genome Projectregulation of protein secretion
GO:0050709
ISO
Genome Projectnegative regulation of protein secretion
GO:0050715
ISO
Genome Projectpositive regulation of cytokine secretion
GO:0050731
IDA
ISO
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0050995
ISO
Genome Projectnegative regulation of lipid catabolic process
GO:0051092
ISO
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051897
ISO
Genome Projectpositive regulation of protein kinase B signaling
GO:0055089
ISO
Genome Projectfatty acid homeostasis
GO:0060070
IGI
Genome Projectcanonical Wnt signaling pathway
GO:0060266
ISO
Genome Projectnegative regulation of respiratory burst involved in inflammatory response
GO:0060267
ISO
Genome Projectpositive regulation of respiratory burst
GO:0070059
IMP
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1900182
ISO
Genome Projectpositive regulation of protein localization to nucleus
GO:2000252
ISO
Genome Projectnegative regulation of feeding behavior
GO:0007257
IDA
Genome Projectactivation of JUN kinase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
ISO
IEA
Genome Projectprotease binding
GO:0005158
ISO
Genome Projectinsulin receptor binding
GO:0005159
ISO
Genome Projectinsulin-like growth factor receptor binding
GO:0005179
ISO
IEA
Genome Projecthormone activity
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0042802
ISO
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005634
IDA
Genome Projectnucleus
GO:0005732
IDA
Genome Projectsmall nucleolar ribonucleoprotein complex
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005829
IDA
Genome Projectcytosol
GO:0030141
IDA
IEA
Genome Projectsecretory granule
GO:0034774
TAS
Genome Projectsecretory granule lumen

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR004825Insulin
IPR016179Insulin-like
IPR022352Insulin family
IPR022353Insulin, conserved site

No MapMan annotations defined for this gene.