Gene: ENSMUSG00000000120 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000000120
Transcript Identifier
ENSMUST00000000122
Gene Type
Coding gene
Location
11 : 95570803-95587558 : negative

Family Information

Homologous gene family
HOM03P025735
(3 genes in 2 species)
specific family

Descriptions

gene_descr
nerve growth factor receptor (TNFR superfamily, member 16)

Identifiers

Type Value
UniprotQ8CFT3
MGI97323

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007411
IMP
Genome Projectaxon guidance
GO:0007417
IMP
Genome Projectcentral nervous system development
GO:0009611
IEA
Genome Projectresponse to wounding
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0010942
IEA
Genome Projectpositive regulation of cell death
GO:0010977
IEA
Genome Projectnegative regulation of neuron projection development
GO:0012501
IDA
Genome Projectprogrammed cell death
GO:0016048
IMP
Genome Projectdetection of temperature stimulus
GO:0019233
IEA
Genome Projectsensory perception of pain
GO:0021675
IMP
Genome Projectnerve development
GO:0031069
IMP
Genome Projecthair follicle morphogenesis
GO:0031643
IEA
Genome Projectpositive regulation of myelination
GO:0032224
IEA
Genome Projectpositive regulation of synaptic transmission, cholinergic
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0034599
IEA
Genome Projectcellular response to oxidative stress
GO:0035025
IEA
Genome Projectpositive regulation of Rho protein signal transduction
GO:0035914
IEA
Genome Projectskeletal muscle cell differentiation
GO:0040037
IMP
Genome Projectnegative regulation of fibroblast growth factor receptor signaling pathway
GO:0042488
IMP
Genome Projectpositive regulation of odontogenesis of dentin-containing tooth
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043410
IEA
Genome Projectpositive regulation of MAPK cascade
GO:0043524
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0043588
IMP
Genome Projectskin development
GO:0048146
IMP
Genome Projectpositive regulation of fibroblast proliferation
GO:0051799
IMP
Genome Projectnegative regulation of hair follicle development
GO:0051897
IEA
Genome Projectpositive regulation of protein kinase B signaling
GO:0051902
IEA
Genome Projectnegative regulation of mitochondrial depolarization
GO:0051968
IEA
Genome Projectpositive regulation of synaptic transmission, glutamatergic
GO:0060548
IEA
Genome Projectnegative regulation of cell death
GO:1901216
IEA
Genome Projectpositive regulation of neuron death
GO:2000377
IEA
Genome Projectregulation of reactive oxygen species metabolic process
GO:2001235
IDA
Genome Projectpositive regulation of apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001540
IEA
Genome Projectbeta-amyloid binding
GO:0005035
IDA
Genome Projectdeath receptor activity
GO:0005168
IEA
Genome Projectneurotrophin TRKA receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0043121
IEA
Genome Projectneurotrophin binding
GO:0048406
IDA
IEA
Genome Projectnerve growth factor binding
GO:0070678
IEA
Genome Projectpreprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005635
IEA
Genome Projectnuclear envelope
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005791
IEA
Genome Projectrough endoplasmic reticulum
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0009897
IEA
Genome Projectexternal side of plasma membrane
GO:0030135
IEA
Genome Projectcoated vesicle
GO:0032590
IEA
Genome Projectdendrite membrane
GO:0032809
IEA
Genome Projectneuronal cell body membrane
GO:0043204
IEA
Genome Projectperikaryon
GO:0045121
IEA
Genome Projectmembrane raft
GO:0045334
IEA
Genome Projectclathrin-coated endocytic vesicle
GO:0097481
IDA
Genome Projectneuronal postsynaptic density

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000488Death domain
IPR001368TNFR/NGFR cysteine-rich region
IPR011029Death-like domain
IPR022325Tumour necrosis factor receptor 16

No MapMan annotations defined for this gene.