Gene: ENSMUSG00000000093 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000000093
Transcript Identifier
ENSMUST00000000095
Gene Type
Coding gene
Location
11 : 85833107-85841014 : positive

Family Information

Homologous gene family
HOM03P001268
(54 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P024319
(4 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
T-box 2

Identifiers

Type Value
UniprotQ60707
MGI98494

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA, IGI
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0003007
IMP
Genome Projectheart morphogenesis
GO:0003148
IMP
Genome Projectoutflow tract septum morphogenesis
GO:0003151
IMP
Genome Projectoutflow tract morphogenesis
GO:0003203
IMP
Genome Projectendocardial cushion morphogenesis
GO:0003256
IDA
Genome Projectregulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007219
IDA
Genome ProjectNotch signaling pathway
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007521
IMP
Genome Projectmuscle cell fate determination
GO:0007569
IDA
ISO
IEA
Genome Projectcell aging
GO:0008284
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0035909
IMP
Genome Projectaorta morphogenesis
GO:0036302
IMP
Genome Projectatrioventricular canal development
GO:0042733
IMP
Genome Projectembryonic digit morphogenesis
GO:0045892
IDA
ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0048596
IMP
Genome Projectembryonic camera-type eye morphogenesis
GO:0048738
IMP
Genome Projectcardiac muscle tissue development
GO:0060021
IMP, IGI
Genome Projectpalate development
GO:0060045
IMP
Genome Projectpositive regulation of cardiac muscle cell proliferation
GO:0060465
IMP
Genome Projectpharynx development
GO:0060560
IMP
Genome Projectdevelopmental growth involved in morphogenesis
GO:0060596
IGI
Genome Projectmammary placode formation
GO:0090398
ISS, ISO
IEA
Genome Projectcellular senescence
GO:1901208
IMP
Genome Projectnegative regulation of heart looping
GO:1901211
IMP
Genome Projectnegative regulation of cardiac chamber formation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
ISO
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078
ISO
IEA
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003700
IDA
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043565
ISO
IEA
Genome Projectsequence-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005667
IDA
Genome Projecttranscription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001699Transcription factor, T-box
IPR002070Transcription factor, Brachyury
IPR008967p53-like transcription factor, DNA-binding
IPR018186Transcription factor, T-box, conserved site
IPR022582Transcription factor, T-box, region of unknown function

No MapMan annotations defined for this gene.