Gene: ENSG00000277807 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000277807
Transcript Identifier
ENST00000612636
Gene Type
Coding gene
Location
CHR_HSCHR19LRC_PGF1_CTG3_1 : 535952-541756 : positive

Family Information

Homologous gene family
HOM03P000078
(332 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P002257
(31 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1

Identifiers

Type Value
pidENSP00000479887
HGNC6605
UniprotQ8NHL6

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001915
IDA
Genome Projectnegative regulation of T cell mediated cytotoxicity
GO:0002230
IDA
Genome Projectpositive regulation of defense response to virus by host
GO:0002250
IEA
Genome Projectadaptive immune response
GO:0002309
IDA
Genome ProjectT cell proliferation involved in immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0002740
IDA
Genome Projectnegative regulation of cytokine secretion involved in immune response
GO:0002767
NAS
Genome Projectimmune response-inhibiting cell surface receptor signaling pathway
GO:0002774
IDA
Genome ProjectFc receptor mediated inhibitory signaling pathway
GO:0007165
IDA
Genome Projectsignal transduction
GO:0009615
IDA
Genome Projectresponse to virus
GO:0010628
IDA
Genome Projectpositive regulation of gene expression
GO:0014063
IDA
Genome Projectnegative regulation of serotonin secretion
GO:0031623
TAS
Genome Projectreceptor internalization
GO:0032609
IDA
Genome Projectinterferon-gamma production
GO:0032689
IDA
Genome Projectnegative regulation of interferon-gamma production
GO:0032945
IDA
Genome Projectnegative regulation of mononuclear cell proliferation
GO:0035548
IDA
Genome Projectnegative regulation of interferon-beta secretion
GO:0042130
IDA
Genome Projectnegative regulation of T cell proliferation
GO:0042536
IDA
Genome Projectnegative regulation of tumor necrosis factor biosynthetic process
GO:0043065
IDA
Genome Projectpositive regulation of apoptotic process
GO:0045077
IDA
Genome Projectnegative regulation of interferon-gamma biosynthetic process
GO:0045786
IDA
Genome Projectnegative regulation of cell cycle
GO:0045806
IDA
Genome Projectnegative regulation of endocytosis
GO:0045919
IDA, IMP
Genome Projectpositive regulation of cytolysis
GO:0045944
NAS
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0045953
IDA
Genome Projectnegative regulation of natural killer cell mediated cytotoxicity
GO:0046636
IDA
Genome Projectnegative regulation of alpha-beta T cell activation
GO:0050776
TAS
Genome Projectregulation of immune response
GO:0051607
IDA
Genome Projectdefense response to virus
GO:0051926
IDA
Genome Projectnegative regulation of calcium ion transport
GO:0071222
IEP
Genome Projectcellular response to lipopolysaccharide
GO:0072643
IDA
Genome Projectinterferon-gamma secretion
GO:0097028
IEP
Genome Projectdendritic cell differentiation
GO:2000669
IDA
Genome Projectnegative regulation of dendritic cell apoptotic process
GO:2001180
IDA
Genome Projectnegative regulation of interleukin-10 secretion
GO:2001183
IDA
Genome Projectnegative regulation of interleukin-12 secretion
GO:2001186
IDA
Genome Projectnegative regulation of CD8-positive, alpha-beta T cell activation
GO:2001189
IDA
Genome Projectnegative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:2001193
IDA
Genome Projectpositive regulation of gamma-delta T cell activation involved in immune response
GO:2001199
IMP
Genome Projectnegative regulation of dendritic cell differentiation
GO:2001202
IDA
Genome Projectnegative regulation of transforming growth factor-beta secretion
GO:2001205
IDA
Genome Projectnegative regulation of osteoclast development

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008157
IPI
Genome Projectprotein phosphatase 1 binding
GO:0030107
IDA
Genome ProjectHLA-A specific inhibitory MHC class I receptor activity
GO:0030109
IDA
Genome ProjectHLA-B specific inhibitory MHC class I receptor activity
GO:0032393
IDA
Genome ProjectMHC class I receptor activity
GO:0042169
IDA
Genome ProjectSH2 domain binding
GO:0042288
IDA, IPI, IMP
Genome ProjectMHC class I protein binding
GO:0042803
IPI
Genome Projectprotein homodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005886
TAS
Genome Projectplasma membrane
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR003599Immunoglobulin subtype
IPR007110Immunoglobulin-like domain
IPR013783Immunoglobulin-like fold

No MapMan annotations defined for this gene.