Gene: ENSG00000277273 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000277273
Transcript Identifier
ENST00000615305
Gene Type
Coding gene
Location
CHR_HSCHR5_2_CTG1_1 : 18156-60301 : positive

Family Information

Homologous gene family
HOM03P000009
(1563 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000827
(43 genes in 38 species)
specific family

Descriptions

gene_descr
cyclin-dependent kinase 7

Identifiers

Type Value
pidENSP00000479116
HGNC1778
UniprotP50613

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000079
TAS
Genome Projectregulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082
TAS
Genome ProjectG1/S transition of mitotic cell cycle
GO:0000086
TAS
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0000718
TAS
Genome Projectnucleotide-excision repair, DNA damage removal
GO:0006281
TAS, IEA
Genome ProjectDNA repair
GO:0006283
TAS
Genome Projecttranscription-coupled nucleotide-excision repair
GO:0006289
TAS
Genome Projectnucleotide-excision repair
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006360
TAS
Genome Projecttranscription from RNA polymerase I promoter
GO:0006361
TAS
Genome Projecttranscription initiation from RNA polymerase I promoter
GO:0006362
TAS
Genome Projecttranscription elongation from RNA polymerase I promoter
GO:0006363
TAS
Genome Projecttermination of RNA polymerase I transcription
GO:0006366
IDA
TAS
Genome Projecttranscription from RNA polymerase II promoter
GO:0006367
TAS
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0006368
TAS
Genome Projecttranscription elongation from RNA polymerase II promoter
GO:0006370
TAS
Genome Project7-methylguanosine mRNA capping
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007049
IEA
Genome Projectcell cycle
GO:0007050
TAS
Genome Projectcell cycle arrest
GO:0008283
TAS
Genome Projectcell proliferation
GO:0010467
TAS
Genome Projectgene expression
GO:0016032
TAS
Genome Projectviral process
GO:0016310
IEA
Genome Projectphosphorylation
GO:0030521
NAS
Genome Projectandrogen receptor signaling pathway
GO:0040029
TAS
Genome Projectregulation of gene expression, epigenetic
GO:0045814
TAS
Genome Projectnegative regulation of gene expression, epigenetic
GO:0045893
NAS
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0050434
TAS
Genome Projectpositive regulation of viral transcription
GO:0051301
IEA
Genome Projectcell division

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003713
NAS
Genome Projecttranscription coactivator activity
GO:0004672
TAS, IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004693
TAS, IEA
Genome Projectcyclin-dependent protein serine/threonine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008022
IPI
Genome Projectprotein C-terminus binding
GO:0008094
IDA
Genome ProjectDNA-dependent ATPase activity
GO:0008353
IDA
IEA
Genome ProjectRNA polymerase II carboxy-terminal domain kinase activity
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0050681
NAS
Genome Projectandrogen receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
TAS, IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005675
IDA
Genome Projectholo TFIIH complex
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IDA
Genome Projectmitochondrion
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.