Gene: ENSG00000276701 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000276701
Transcript Identifier
ENST00000613839
Gene Type
Coding gene
Location
CHR_HSCHR22_1_CTG7 : 130837-131468 : positive

Family Information

Homologous gene family
HOM03P002612
(35 genes in 25 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
macrophage migration inhibitory factor (glycosylation-inhibiting factor)

Identifiers

Type Value
pidENSP00000482779
HGNC7097
UniprotP14174
UniprotI4AY87

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001934
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0002906
IEA
Genome Projectnegative regulation of mature B cell apoptotic process
GO:0007569
IEA
Genome Projectcell aging
GO:0030330
IEA
Genome ProjectDNA damage response, signal transduction by p53 class mediator
GO:0031666
IEA
Genome Projectpositive regulation of lipopolysaccharide-mediated signaling pathway
GO:0032269
IEA
Genome Projectnegative regulation of cellular protein metabolic process
GO:0033033
IEA
Genome Projectnegative regulation of myeloid cell apoptotic process
GO:0042127
IEA
Genome Projectregulation of cell proliferation
GO:0043406
IEA
Genome Projectpositive regulation of MAP kinase activity
GO:0061078
IEA
Genome Projectpositive regulation of prostaglandin secretion involved in immune response
GO:0061081
IEA
Genome Projectpositive regulation of myeloid leukocyte cytokine production involved in immune response
GO:0090238
IEA
Genome Projectpositive regulation of arachidonic acid secretion
GO:2000343
IEA
Genome Projectpositive regulation of chemokine (C-X-C motif) ligand 2 production
GO:0001516
IDA
Genome Projectprostaglandin biosynthetic process
GO:0002376
IEA
Genome Projectimmune system process
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007166
IDA
Genome Projectcell surface receptor signaling pathway
GO:0008283
IDA
Genome Projectcell proliferation
GO:0010629
IDA
Genome Projectnegative regulation of gene expression
GO:0010739
IDA
Genome Projectpositive regulation of protein kinase A signaling
GO:0019752
IDA
Genome Projectcarboxylic acid metabolic process
GO:0030890
IDA
Genome Projectpositive regulation of B cell proliferation
GO:0033138
IDA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0042327
IDA
Genome Projectpositive regulation of phosphorylation
GO:0043030
NAS
Genome Projectregulation of macrophage activation
GO:0043066
IDA
Genome Projectnegative regulation of apoptotic process
GO:0043518
IDA
Genome Projectnegative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045087
IEA
Genome Projectinnate immune response
GO:0048146
IDA
Genome Projectpositive regulation of fibroblast proliferation
GO:0050715
IDA
Genome Projectpositive regulation of cytokine secretion
GO:0050731
IDA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0050918
IDA
Genome Projectpositive chemotaxis
GO:0070207
IPI
Genome Projectprotein homotrimerization
GO:0070374
IDA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071157
IDA
Genome Projectnegative regulation of cell cycle arrest
GO:0090344
IDA
Genome Projectnegative regulation of cell aging
GO:1902166
IDA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0004167
IDA
IEA
Genome Projectdopachrome isomerase activity
GO:0005102
IPI
Genome Projectreceptor binding
GO:0005125
IDA
IEA
Genome Projectcytokine activity
GO:0005126
IPI
Genome Projectcytokine receptor binding
GO:0016853
IEA
Genome Projectisomerase activity
GO:0042056
IDA
Genome Projectchemoattractant activity
GO:0050178
IDA
IEA
Genome Projectphenylpyruvate tautomerase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
IEA
Genome Projectextracellular space
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0043209
IEA
Genome Projectmyelin sheath
GO:0005576
IDA
IEA
Genome Projectextracellular region
GO:0009986
IDA
Genome Projectcell surface
GO:0031982
IDA
Genome Projectvesicle
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001398Macrophage migration inhibitory factor
IPR019829Macrophage migration inhibitory factor, conserved site
IPR014347Tautomerase/MIF superfamily

No MapMan annotations defined for this gene.