Gene: ENSG00000275824 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000275824
Transcript Identifier
ENST00000617322
Gene Type
Coding gene
Location
CHR_HSCHR17_7_CTG4 : 338827-340233 : positive

Family Information

Homologous gene family
HOM03P003119
(31 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P022683
(4 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
chemokine (C-C motif) ligand 4

Identifiers

Type Value
pidENSP00000480345
HGNC10630
UniprotP13236

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002548
IBA
Genome Projectmonocyte chemotaxis
GO:0006928
TAS
Genome Projectmovement of cell or subcellular component
GO:0006935
IEA
Genome Projectchemotaxis
GO:0006954
TAS, IEA
Genome Projectinflammatory response
GO:0006955
TAS, IEA
Genome Projectimmune response
GO:0006955
IEA
InterProimmune response
GO:0007155
TAS
Genome Projectcell adhesion
GO:0007163
TAS
Genome Projectestablishment or maintenance of cell polarity
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007186
IBA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007267
TAS
Genome Projectcell-cell signaling
GO:0009615
TAS
Genome Projectresponse to virus
GO:0009636
IDA
Genome Projectresponse to toxic substance
GO:0030593
IBA
Genome Projectneutrophil chemotaxis
GO:0043547
IBA
Genome Projectpositive regulation of GTPase activity
GO:0043922
IDA
Genome Projectnegative regulation by host of viral transcription
GO:0048245
IBA
Genome Projecteosinophil chemotaxis
GO:0050729
IBA
Genome Projectpositive regulation of inflammatory response
GO:0050850
IMP
Genome Projectpositive regulation of calcium-mediated signaling
GO:0051928
IDA
Genome Projectpositive regulation of calcium ion transport
GO:0070098
IBA
Genome Projectchemokine-mediated signaling pathway
GO:0070374
IBA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071346
IBA
Genome Projectcellular response to interferon-gamma
GO:0071347
IBA
Genome Projectcellular response to interleukin-1
GO:0071356
IBA
Genome Projectcellular response to tumor necrosis factor
GO:2000503
IDA
Genome Projectpositive regulation of natural killer cell chemotaxis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
TAS, IEA
Genome Projectcytokine activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008009
TAS, IEA
Genome Projectchemokine activity
GO:0008009
IEA
InterProchemokine activity
GO:0031726
IPI
Genome ProjectCCR1 chemokine receptor binding
GO:0031730
IPI
Genome ProjectCCR5 chemokine receptor binding
GO:0042802
IPI
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005576
IEA
InterProextracellular region
GO:0005615
TAS, IEA
Genome Projectextracellular space

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001811Chemokine interleukin-8-like domain
IPR000827CC chemokine, conserved site

No MapMan annotations defined for this gene.