Gene: ENSG00000275565 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000275565
Transcript Identifier
ENST00000610656
Gene Type
Coding gene
Location
CHR_HSCHR10_1_CTG2 : 215111-286518 : positive

Family Information

Homologous gene family
HOM03P000704
(78 genes in 15 species)
specific family
Orthologous gene family
ORTHO03P000181
(65 genes in 15 species)
specific family

Descriptions

gene_descr
arachidonate 5-lipoxygenase

Identifiers

Type Value
pidENSP00000484468
HGNC435
UniprotP09917

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002526
IEA
Genome Projectacute inflammatory response
GO:0002540
IEA
Genome Projectleukotriene production involved in inflammatory response
GO:0006691
TAS, IEA
Genome Projectleukotriene metabolic process
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0019233
IEA
Genome Projectsensory perception of pain
GO:0019369
TAS, IEA
Genome Projectarachidonic acid metabolic process
GO:0019370
IDA
IEA
Genome Projectleukotriene biosynthetic process
GO:0019372
TAS, IEA
Genome Projectlipoxygenase pathway
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045907
IEA
Genome Projectpositive regulation of vasoconstriction
GO:0055093
IEA
Genome Projectresponse to hyperoxia
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0055114
IEA
InterProoxidation-reduction process
GO:2001300
TAS
Genome Projectlipoxin metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004051
IDA
TAS, IEA
Genome Projectarachidonate 5-lipoxygenase activity
GO:0005506
IDA
IEA
Genome Projectiron ion binding
GO:0005506
IEA
InterProiron ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005515
IEA
InterProprotein binding
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016702
IEA
Genome Projectoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0016702
IEA
InterProoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046872
IEA
InterPrometal ion binding
GO:0051213
IEA
Genome Projectdioxygenase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
IDA
Genome Projectextracellular space
GO:0005634
IEA
Genome Projectnucleus
GO:0005635
IDA
TAS
Genome Projectnuclear envelope
GO:0005641
IDA
Genome Projectnuclear envelope lumen
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0016020
IEA
Genome Projectmembrane
GO:0016363
IDA
IEA
Genome Projectnuclear matrix
GO:0030425
IEA
Genome Projectdendrite
GO:0031965
IDA
IEA
Genome Projectnuclear membrane
GO:0042383
IEA
Genome Projectsarcolemma

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001024PLAT/LH2 domain
IPR013819Lipoxygenase, C-terminal
IPR001885Lipoxygenase, mammalian
IPR020833Lipoxygenase, iron binding site
IPR020834Lipoxygenase, conserved site

No MapMan annotations defined for this gene.