Gene: ENSG00000274829 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000274829
Transcript Identifier
ENST00000615183
Gene Type
Coding gene
Location
CHR_HSCHR16_1_CTG1 : 9574-202981 : negative

Family Information

Homologous gene family
HOM03P003312
(29 genes in 20 species)
specific family
Orthologous gene family
ORTHO03P004471
(19 genes in 18 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
poly(A)-specific ribonuclease

Identifiers

Type Value
pidENSP00000478668
HGNC8609
UniprotO95453

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000184
IMP
IEA
Genome Projectnuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000288
TAS
Genome Projectnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289
TAS
Genome Projectnuclear-transcribed mRNA poly(A) tail shortening
GO:0006402
IEA
Genome ProjectmRNA catabolic process
GO:0006402
IEA
InterPromRNA catabolic process
GO:0007292
TAS
Genome Projectfemale gamete generation
GO:0009451
TAS
Genome ProjectRNA modification
GO:0010467
TAS
Genome Projectgene expression
GO:0090305
TAS, IEA
Genome Projectnucleic acid phosphodiester bond hydrolysis
GO:0090503
TAS, IEA
Genome ProjectRNA phosphodiester bond hydrolysis, exonucleolytic

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0000166
IEA
InterPronucleotide binding
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003676
IEA
InterPronucleic acid binding
GO:0003723
IEA
Genome ProjectRNA binding
GO:0003723
IEA
InterProRNA binding
GO:0003730
TAS
Genome ProjectmRNA 3'-UTR binding
GO:0004518
TAS, IEA
Genome Projectnuclease activity
GO:0004527
IEA
Genome Projectexonuclease activity
GO:0004535
TAS, IEA
Genome Projectpoly(A)-specific ribonuclease activity
GO:0004535
IEA
InterPropoly(A)-specific ribonuclease activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046872
IEA
InterPrometal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
TAS, IEA
Genome Projectnucleus
GO:0005634
IEA
InterPronucleus
GO:0005730
IEA
Genome Projectnucleolus
GO:0005737
TAS, IEA
Genome Projectcytoplasm
GO:0005737
IEA
InterProcytoplasm
GO:0005829
TAS
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR012677Nucleotide-binding alpha-beta plait domain
IPR012337Ribonuclease H-like domain
IPR001374R3H domain
IPR006941Ribonuclease CAF1
IPR014789Poly(A)-specific ribonuclease, RNA-binding

No MapMan annotations defined for this gene.