Gene: ENSG00000273079 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000273079
Transcript Identifier
ENST00000609686
Gene Type
Coding gene
Location
12 : 13562783-13866208 : negative

Family Information

Homologous gene family
HOM03P000932
(65 genes in 7 species)
specific family

Descriptions

gene_descr
glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Identifiers

Type Value
pidENSP00000477455
HGNC4586
UniprotQ13224

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001662
IEA
Genome Projectbehavioral fear response
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001964
IEA
Genome Projectstartle response
GO:0001967
IEA
Genome Projectsuckling behavior
GO:0006810
TAS, IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006812
IEA
Genome Projectcation transport
GO:0006816
IEA
Genome Projectcalcium ion transport
GO:0007215
TAS
Genome Projectglutamate receptor signaling pathway
GO:0007268
TAS, IEA
Genome Projectsynaptic transmission
GO:0007411
TAS
Genome Projectaxon guidance
GO:0007423
IEA
Genome Projectsensory organ development
GO:0007611
TAS
Genome Projectlearning or memory
GO:0007612
IEA
Genome Projectlearning
GO:0007613
IEA
Genome Projectmemory
GO:0010738
IEA
Genome Projectregulation of protein kinase A signaling
GO:0035235
TAS, IEA
Genome Projectionotropic glutamate receptor signaling pathway
GO:0042596
IEA
Genome Projectfear response
GO:0045471
IDA
Genome Projectresponse to ethanol
GO:0048013
TAS
Genome Projectephrin receptor signaling pathway
GO:0048167
IEA
Genome Projectregulation of synaptic plasticity
GO:0048266
IEA
Genome Projectbehavioral response to pain
GO:0050966
IEA
Genome Projectdetection of mechanical stimulus involved in sensory perception of pain
GO:0060078
IEA
Genome Projectregulation of postsynaptic membrane potential
GO:0060079
IEA
Genome Projectexcitatory postsynaptic potential
GO:0060291
IEA
Genome Projectlong-term synaptic potentiation
GO:0070588
IEA
Genome Projectcalcium ion transmembrane transport
GO:0098655
IEA
Genome Projectcation transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004872
IEA
Genome Projectreceptor activity
GO:0004970
IEA
Genome Projectionotropic glutamate receptor activity
GO:0004972
TAS, IEA
Genome ProjectNMDA glutamate receptor activity
GO:0005216
IEA
Genome Projection channel activity
GO:0005234
IEA
Genome Projectextracellular-glutamate-gated ion channel activity
GO:0005261
IEA
Genome Projectcation channel activity
GO:0005262
IEA
Genome Projectcalcium channel activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
ISS
Genome Projectzinc ion binding
GO:0016594
IDA
Genome Projectglycine binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0008021
IEA
Genome Projectsynaptic vesicle
GO:0009986
ISS
Genome Projectcell surface
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0017146
IDA
Genome ProjectNMDA selective glutamate receptor complex
GO:0030054
IEA
Genome Projectcell junction
GO:0043005
ISS
Genome Projectneuron projection
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane
GO:0097481
IEA
Genome Projectneuronal postsynaptic density

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001320Ionotropic glutamate receptor
IPR001508Ionotropic glutamate receptor, metazoa
IPR001828Receptor, ligand binding region
IPR018884Glutamate [NMDA] receptor, epsilon subunit, C-terminal
IPR019594Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
IPR028082Periplasmic binding protein-like I

No MapMan annotations defined for this gene.