Gene: ENSG00000267534 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000267534
Transcript Identifier
ENST00000590320
Gene Type
Coding gene
Location
19 : 10223844-10224905 : negative

Family Information

Homologous gene family
HOM03P003657
(26 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P075112
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
sphingosine-1-phosphate receptor 2

Identifiers

Type Value
pidENSP00000466933
HGNC3169
UniprotO95136
UniprotA0A024R7B2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003376
IMP
IEA
Genome Projectsphingosine-1-phosphate signaling pathway
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
TAS, IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0010800
IMP
IEA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0090394
IEA
Genome Projectnegative regulation of excitatory postsynaptic potential
GO:0000187
TAS
Genome Projectactivation of MAPK activity
GO:0008284
TAS
Genome Projectpositive regulation of cell proliferation
GO:0031532
IMP
Genome Projectactin cytoskeleton reorganization
GO:0046847
IMP
Genome Projectfilopodium assembly
GO:1903142
IMP
Genome Projectpositive regulation of establishment of endothelial barrier

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
TAS, IEA
Genome ProjectG-protein coupled receptor activity
GO:0038036
IMP
IEA
Genome Projectsphingosine-1-phosphate receptor activity
GO:0001664
IPI
Genome ProjectG-protein coupled receptor binding
GO:0005178
IPI
Genome Projectintegrin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008289
TAS
Genome Projectlipid binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR004061Sphingosine 1-phosphate receptor
IPR004063EDG-5 sphingosine 1-phosphate receptor
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.