Gene: ENSG00000263528 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000263528
Transcript Identifier
ENST00000581977
Gene Type
Coding gene
Location
1 : 206473228-206496145 : positive

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P019066
(5 genes in 3 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon

Identifiers

Type Value
pidENSP00000464030
HGNC14552
UniprotQ14164

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002756
TAS
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0006468
IDA
IEA
Genome Projectprotein phosphorylation
GO:0006955
NAS
Genome Projectimmune response
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007252
IEA
Genome ProjectI-kappaB phosphorylation
GO:0008630
IMP
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0016310
IEA
Genome Projectphosphorylation
GO:0032480
TAS
Genome Projectnegative regulation of type I interferon production
GO:0034138
TAS
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034142
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0035456
IMP
Genome Projectresponse to interferon-beta
GO:0035666
TAS
Genome ProjectTRIF-dependent toll-like receptor signaling pathway
GO:0038061
IDA
Genome ProjectNIK/NF-kappaB signaling
GO:0043123
IEP
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087
TAS
Genome Projectinnate immune response
GO:0051260
IDA
Genome Projectprotein homooligomerization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004704
IDA
Genome ProjectNF-kappaB-inducing kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008384
IEA
Genome ProjectIkappaB kinase activity
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0036435
IMP
Genome ProjectK48-linked polyubiquitin binding
GO:0070530
IMP
Genome ProjectK63-linked polyubiquitin binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0010008
TAS
Genome Projectendosome membrane
GO:0016605
IDA
IEA
Genome ProjectPML body
GO:0031966
IMP
Genome Projectmitochondrial membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.