Gene: ENSG00000247596 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000247596
Transcript Identifier
ENST00000305533
Gene Type
Coding gene
Location
3 : 52229034-52239016 : negative

Family Information

Homologous gene family
HOM03P008383
(10 genes in 9 species)
specific family

Descriptions

gene_descr
twinfilin actin binding protein 2

Identifiers

Type Value
pidENSP00000303908
HGNC9621
UniprotQ6IBS0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0010592
IMP
Genome Projectpositive regulation of lamellipodium assembly
GO:0010976
IMP
Genome Projectpositive regulation of neuron projection development
GO:0030030
IEA
Genome Projectcell projection organization
GO:0030837
ISS
IEA
Genome Projectnegative regulation of actin filament polymerization
GO:0032532
IC
Genome Projectregulation of microvillus length
GO:0032956
IMP
Genome Projectregulation of actin cytoskeleton organization
GO:0042989
ISS
IEA
Genome Projectsequestering of actin monomers
GO:0045773
IMP
Genome Projectpositive regulation of axon extension
GO:0051016
ISS
IEA
Genome Projectbarbed-end actin filament capping
GO:0071300
IMP
Genome Projectcellular response to retinoic acid
GO:0071363
IMP
Genome Projectcellular response to growth factor stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003779
IEA
Genome Projectactin binding
GO:0003785
ISS
IEA
Genome Projectactin monomer binding
GO:0005080
IPI
Genome Projectprotein kinase C binding
GO:0005524
IDA
Genome ProjectATP binding
GO:0005546
ISS
IEA
Genome Projectphosphatidylinositol-4,5-bisphosphate binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IEA
Genome Projectintracellular
GO:0005737
NAS, IEA
Genome Projectcytoplasm
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0030016
ISS
IEA
Genome Projectmyofibril
GO:0030027
ISS
IEA
Genome Projectlamellipodium
GO:0030175
ISS
IEA
Genome Projectfilopodium
GO:0030426
IDA
Genome Projectgrowth cone
GO:0032420
ISS
IEA
Genome Projectstereocilium
GO:0042995
IEA
Genome Projectcell projection
GO:0048471
ISS
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002108Actin-depolymerising factor homology domain
IPR028458Twinfilin
IPR029006ADF-H/Gelsolin-like domain

No MapMan annotations defined for this gene.