Gene: ENSG00000245848 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000245848
Transcript Identifier
ENST00000498907
Gene Type
Coding gene
Location
19 : 33301338-33302414 : negative

Family Information

Homologous gene family
HOM03P036107
(2 genes in 2 species)
specific family

Descriptions

gene_descr
CCAAT/enhancer binding protein (C/EBP), alpha

Identifiers

Type Value
pidENSP00000427514
HGNC1833
UniprotP49715

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000050
IEA
Genome Projecturea cycle
GO:0000122
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001889
ISS
IEA
Genome Projectliver development
GO:0001892
IEA
Genome Projectembryonic placenta development
GO:0006091
TAS
Genome Projectgeneration of precursor metabolites and energy
GO:0006351
IDA
NAS, IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006360
IDA
Genome Projecttranscription from RNA polymerase I promoter
GO:0006366
TAS, IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006953
IEA
Genome Projectacute-phase response
GO:0007005
IEA
Genome Projectmitochondrion organization
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0008203
IEA
Genome Projectcholesterol metabolic process
GO:0008285
IDA
ISS
IEA
Genome Projectnegative regulation of cell proliferation
GO:0016032
IEA
Genome Projectviral process
GO:0019221
NAS
Genome Projectcytokine-mediated signaling pathway
GO:0030099
NAS, IEA
Genome Projectmyeloid cell differentiation
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030225
IEA
Genome Projectmacrophage differentiation
GO:0030324
ISS
IEA
Genome Projectlung development
GO:0030851
ISS
IEA
Genome Projectgranulocyte differentiation
GO:0031100
IEA
Genome Projectorgan regeneration
GO:0032436
TAS
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033274
IEA
Genome Projectresponse to vitamin B2
GO:0042127
IEA
Genome Projectregulation of cell proliferation
GO:0042593
ISS
IEA
Genome Projectglucose homeostasis
GO:0045444
ISS
IEA
Genome Projectfat cell differentiation
GO:0045600
IEA
Genome Projectpositive regulation of fat cell differentiation
GO:0045669
IEA
Genome Projectpositive regulation of osteoblast differentiation
GO:0045736
TAS
Genome Projectnegative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045786
IEA
Genome Projectnegative regulation of cell cycle
GO:0045892
ISS
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA, IMP
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0045945
IDA
Genome Projectpositive regulation of transcription from RNA polymerase III promoter
GO:0048469
IEA
Genome Projectcell maturation
GO:0048839
IEA
Genome Projectinner ear development
GO:0050872
IEA
Genome Projectwhite fat cell differentiation
GO:0050873
IEA
Genome Projectbrown fat cell differentiation
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0055088
ISS
IEA
Genome Projectlipid homeostasis
GO:0071285
IEA
Genome Projectcellular response to lithium ion
GO:0071407
IEA
Genome Projectcellular response to organic cyclic compound

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001013
IDA
Genome ProjectRNA polymerase I regulatory region DNA binding
GO:0001077
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001228
IMP
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003677
TAS, IEA
Genome ProjectDNA binding
GO:0003700
IDA
TAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
NAS, IEA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003713
ISS
IEA
Genome Projecttranscription coactivator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
IEA
Genome Projecttranscription factor binding
GO:0019900
IPI
Genome Projectkinase binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0042803
ISS
IEA
Genome Projectprotein homodimerization activity
GO:0042826
IEA
Genome Projecthistone deacetylase binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity
GO:0071837
IEA
Genome ProjectHMG box domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
NAS, IEA
Genome Projectnucleus
GO:0005667
IEA
Genome Projecttranscription factor complex
GO:0005730
IDA
IEA
Genome Projectnucleolus
GO:0016363
IEA
Genome Projectnuclear matrix
GO:0035189
IEA
Genome ProjectRb-E2F complex
GO:0036488
IEA
Genome ProjectCHOP-C/EBP complex
GO:0043234
IEA
Genome Projectprotein complex
GO:0090575
IMP
Genome ProjectRNA polymerase II transcription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004827Basic-leucine zipper domain
IPR016468CCAAT/enhancer-binding protein, chordates
IPR031106CCAAT/enhancer-binding protein C/EBP

No MapMan annotations defined for this gene.