Gene: ENSG00000237582 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000237582
Transcript Identifier
ENST00000437747
Gene Type
Coding gene
Location
CHR_HSCHR6_MHC_SSTO_CTG1 : 2468017-2474052 : negative

Family Information

Homologous gene family
HOM03P002304
(39 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P012387
(7 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
POU class 5 homeobox 1

Identifiers

Type Value
pidENSP00000391681
HGNC9221
UniprotQ01860
UniprotD2IYK3

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IDA
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0010628
ISS
Genome Projectpositive regulation of gene expression
GO:0010629
ISS
Genome Projectnegative regulation of gene expression
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001714
IDA
Genome Projectendodermal cell fate specification
GO:0001824
ISS
Genome Projectblastocyst development
GO:0003130
IMP
Genome ProjectBMP signaling pathway involved in heart induction
GO:0006366
ISS
Genome Projecttranscription from RNA polymerase II promoter
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0009611
IEP
Genome Projectresponse to wounding
GO:0009653
TAS
Genome Projectanatomical structure morphogenesis
GO:0009786
ISS
Genome Projectregulation of asymmetric cell division
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0035019
IDA, IMP
TAS
Genome Projectsomatic stem cell population maintenance
GO:0035413
IDA
Genome Projectpositive regulation of catenin import into nucleus
GO:0042789
ISS
Genome ProjectmRNA transcription from RNA polymerase II promoter
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0060391
IDA
Genome Projectpositive regulation of SMAD protein import into nucleus
GO:0060795
IMP
Genome Projectcell fate commitment involved in formation of primary germ layer
GO:0060913
IDA
Genome Projectcardiac cell fate determination
GO:0060965
IMP
Genome Projectnegative regulation of gene silencing by miRNA
GO:0090081
IMP
Genome Projectregulation of heart induction by regulation of canonical Wnt signaling pathway
GO:0090308
IDA
Genome Projectregulation of methylation-dependent chromatin silencing

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001158
ISS
Genome Projectenhancer sequence-specific DNA binding
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003700
IDA
TAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0019955
ISS
Genome Projectcytokine binding
GO:0043565
IDA
IEA
Genome Projectsequence-specific DNA binding
GO:0000976
IDA
Genome Projecttranscription regulatory region sequence-specific DNA binding
GO:0000981
ISS
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001227
IDA
Genome Projecttranscriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0035198
IDA
Genome ProjectmiRNA binding
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
ISS
Genome Projectnuclear chromatin
GO:0005634
IDA
IC, IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005667
IDA
Genome Projecttranscription factor complex
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
IDA
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000327POU-specific domain
IPR001356Homeobox domain
IPR009057Homeodomain-like
IPR010982Lambda repressor-like, DNA-binding domain
IPR013847POU domain
IPR015585POU domain-containing protein, class 5
IPR017970Homeobox, conserved site

No MapMan annotations defined for this gene.