Gene: ENSG00000234370 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000234370
Transcript Identifier
ENST00000416773
Gene Type
Coding gene
Location
CHR_HSCHR6_MHC_MCF_CTG1 : 2253184-2258130 : positive

Family Information

Homologous gene family
HOM03P001762
(45 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P001494
(37 genes in 34 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
general transcription factor IIH, polypeptide 4, 52kDa

Identifiers

Type Value
pidENSP00000399554
HGNC4658
UniprotQ92759

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000718
TAS
Genome Projectnucleotide-excision repair, DNA damage removal
GO:0006281
TAS, IEA
Genome ProjectDNA repair
GO:0006283
TAS
Genome Projecttranscription-coupled nucleotide-excision repair
GO:0006289
IBA
TAS, IEA
Genome Projectnucleotide-excision repair
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006360
TAS
Genome Projecttranscription from RNA polymerase I promoter
GO:0006361
TAS
Genome Projecttranscription initiation from RNA polymerase I promoter
GO:0006362
TAS
Genome Projecttranscription elongation from RNA polymerase I promoter
GO:0006363
TAS
Genome Projecttermination of RNA polymerase I transcription
GO:0006366
IDA
TAS
Genome Projecttranscription from RNA polymerase II promoter
GO:0006367
TAS
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0006368
TAS
Genome Projecttranscription elongation from RNA polymerase II promoter
GO:0006370
TAS
Genome Project7-methylguanosine mRNA capping
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0010467
TAS
Genome Projectgene expression
GO:0016032
TAS
Genome Projectviral process
GO:0032508
IEA
Genome ProjectDNA duplex unwinding
GO:0040029
TAS
Genome Projectregulation of gene expression, epigenetic
GO:0045814
TAS
Genome Projectnegative regulation of gene expression, epigenetic
GO:0050434
TAS
Genome Projectpositive regulation of viral transcription
GO:0070816
IBA
Genome Projectphosphorylation of RNA polymerase II C-terminal domain

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003690
IBA
Genome Projectdouble-stranded DNA binding
GO:0003700
TAS
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0004003
IEA
Genome ProjectATP-dependent DNA helicase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0004672
IDA
Genome Projectprotein kinase activity
GO:0008094
IDA
Genome ProjectDNA-dependent ATPase activity
GO:0008353
IDA
Genome ProjectRNA polymerase II carboxy-terminal domain kinase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000439
IBA
IEA
Genome Projectcore TFIIH complex
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005675
IDA
Genome Projectholo TFIIH complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004598Transcription factor TFIIH subunit p52/Tfb2

No MapMan annotations defined for this gene.