Gene: ENSG00000230143 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000230143
Transcript Identifier
ENST00000444632
Gene Type
Coding gene
Location
CHR_HSCHR6_MHC_SSTO_CTG1 : 2028902-2042985 : negative

Family Information

Homologous gene family
HOM03P005748
(16 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P011995
(7 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
flotillin 1

Identifiers

Type Value
pidENSP00000388861
HGNC3757
UniprotO75955
UniprotQ5ST80

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001765
IMP
Genome Projectmembrane raft assembly
GO:0001819
IMP
Genome Projectpositive regulation of cytokine production
GO:0001934
IMP
Genome Projectpositive regulation of protein phosphorylation
GO:0002090
IMP
Genome Projectregulation of receptor internalization
GO:0007409
IEA
Genome Projectaxonogenesis
GO:0022617
IMP
Genome Projectextracellular matrix disassembly
GO:0032092
IMP
Genome Projectpositive regulation of protein binding
GO:0032226
ISS
Genome Projectpositive regulation of synaptic transmission, dopaminergic
GO:0032728
IMP
Genome Projectpositive regulation of interferon-beta production
GO:0033227
IMP
Genome ProjectdsRNA transport
GO:0034116
IMP
Genome Projectpositive regulation of heterotypic cell-cell adhesion
GO:0034141
IMP
Genome Projectpositive regulation of toll-like receptor 3 signaling pathway
GO:0034976
IMP
Genome Projectresponse to endoplasmic reticulum stress
GO:0035023
IEA
Genome Projectregulation of Rho protein signal transduction
GO:0044854
IMP
Genome Projectplasma membrane raft assembly
GO:0045807
IMP
Genome Projectpositive regulation of endocytosis
GO:0048643
IMP
Genome Projectpositive regulation of skeletal muscle tissue development
GO:0051260
IMP
Genome Projectprotein homooligomerization
GO:0060355
IMP
Genome Projectpositive regulation of cell adhesion molecule production
GO:0070528
IMP
Genome Projectprotein kinase C signaling
GO:0071360
IMP
Genome Projectcellular response to exogenous dsRNA
GO:0072659
IEA
Genome Projectprotein localization to plasma membrane
GO:0090002
IMP
Genome Projectestablishment of protein localization to plasma membrane
GO:1901741
IMP
Genome Projectpositive regulation of myoblast fusion
GO:1901890
IMP
Genome Projectpositive regulation of cell junction assembly
GO:1903044
IMP
Genome Projectprotein localization to membrane raft
GO:2000049
IMP
Genome Projectpositive regulation of cell-cell adhesion mediated by cadherin
GO:0034143
IMP
Genome Projectregulation of toll-like receptor 4 signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
IPI
Genome Projectprotease binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0046982
IMP
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001931
IDA
Genome Projecturopod
GO:0005765
IDA
Genome Projectlysosomal membrane
GO:0005768
IDA
IEA
Genome Projectendosome
GO:0005769
IDA
Genome Projectearly endosome
GO:0005815
IDA
Genome Projectmicrotubule organizing center
GO:0005886
IDA, IMP
IEA
Genome Projectplasma membrane
GO:0005901
TAS, IEA
Genome Projectcaveola
GO:0005913
IDA
Genome Projectcell-cell adherens junction
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016021
TAS
Genome Projectintegral component of membrane
GO:0016323
IDA
Genome Projectbasolateral plasma membrane
GO:0016600
IDA
IEA
Genome Projectflotillin complex
GO:0030027
IDA
Genome Projectlamellipodium
GO:0031410
IDA
Genome Projectcytoplasmic vesicle
GO:0034451
IDA
Genome Projectcentriolar satellite
GO:0042383
IEA
Genome Projectsarcolemma
GO:0042470
IEA
Genome Projectmelanosome
GO:0044291
IDA
Genome Projectcell-cell contact zone
GO:0045121
IDA
Genome Projectmembrane raft
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0008180
IDA
Genome ProjectCOP9 signalosome
GO:0030864
IDA
Genome Projectcortical actin cytoskeleton

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001107Band 7 domain
IPR027705Flotillin family
IPR031905Flotillin, C-terminal domain

No MapMan annotations defined for this gene.