Gene: ENSG00000227277 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000227277
Transcript Identifier
ENST00000445885
Gene Type
Coding gene
Location
CHR_HSCHR6_MHC_SSTO_CTG1 : 3494719-3496533 : positive

Family Information

Homologous gene family
HOM03P000785
(73 genes in 34 species)
specific family
Orthologous gene family
ORTHO03P009997
(8 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
ring finger protein 5, E3 ubiquitin protein ligase

Identifiers

Type Value
pidENSP00000401172
HGNC10068
UniprotQ99942
UniprotA0A024RCQ4

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009617
IEA
Genome Projectresponse to bacterium
GO:0010507
IEA
Genome Projectnegative regulation of autophagy
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0031648
IEA
Genome Projectprotein destabilization
GO:2000785
IEA
Genome Projectregulation of autophagosome assembly
GO:0036503
IMP, IGI
Genome ProjectERAD pathway
GO:0044257
IMP
Genome Projectcellular protein catabolic process
GO:0070534
IDA
Genome Projectprotein K63-linked ubiquitination
GO:0070936
IDA
Genome Projectprotein K48-linked ubiquitination
GO:0071712
IMP
Genome ProjectER-associated misfolded protein catabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008270
TAS, IEA
Genome Projectzinc ion binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0004842
IDA
Genome Projectubiquitin-protein transferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016874
IEA
Genome Projectligase activity
GO:1904264
TAS
Genome Projectubiquitin protein ligase activity involved in ERAD pathway

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016020
IEA
Genome Projectmembrane
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031966
IEA
Genome Projectmitochondrial membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR017907Zinc finger, RING-type, conserved site

No MapMan annotations defined for this gene.